http://purl.uniprot.org/citations/2524646 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/2524646 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/2524646 | http://www.w3.org/2000/01/rdf-schema#comment | "The sulfur-regulatory circuit of Neurospora crassa consists of a set of unlinked structural genes which encode sulfur-catabolic enzymes and two major regulatory genes which govern their expression. The positive-acting cys-3 regulatory gene is required to turn on the expression of the sulfur-related enzymes, whereas the other regulatory gene, scon, acts in a negative fashion to repress the synthesis of the same set of enzymes. Expression of the cys-3 regulatory gene was found to be controlled by scon and by sulfur availability. The nucleotide sequence of the cys-3 gene was determined and can be translated to yield a protein of molecular weight 25,892 which displays significant homology with the oncogene protein Fos, yeast GCN4 protein, and sea urchin histone H1. Moreover, the putative cys-3 protein has a well-defined leucine zipper element plus an adjacent charged region which together may make up a DNA-binding site. A cys-3 mutant and a cys-3 temperature-sensitive mutant lead to substitutions of glutamine for basic amino acids within the charged region and thus may alter DNA-binding properties of the cys-3 protein."xsd:string |
http://purl.uniprot.org/citations/2524646 | http://purl.org/dc/terms/identifier | "doi:10.1128/mcb.9.3.1120-1127.1989"xsd:string |
http://purl.uniprot.org/citations/2524646 | http://purl.org/dc/terms/identifier | "doi:10.1128/mcb.9.3.1120-1127.1989"xsd:string |
http://purl.uniprot.org/citations/2524646 | http://purl.uniprot.org/core/author | "Marzluf G.A."xsd:string |
http://purl.uniprot.org/citations/2524646 | http://purl.uniprot.org/core/author | "Marzluf G.A."xsd:string |
http://purl.uniprot.org/citations/2524646 | http://purl.uniprot.org/core/author | "Paietta J.V."xsd:string |
http://purl.uniprot.org/citations/2524646 | http://purl.uniprot.org/core/author | "Paietta J.V."xsd:string |
http://purl.uniprot.org/citations/2524646 | http://purl.uniprot.org/core/author | "Fu Y.-H."xsd:string |
http://purl.uniprot.org/citations/2524646 | http://purl.uniprot.org/core/author | "Fu Y.-H."xsd:string |
http://purl.uniprot.org/citations/2524646 | http://purl.uniprot.org/core/author | "Mannix D.G."xsd:string |
http://purl.uniprot.org/citations/2524646 | http://purl.uniprot.org/core/author | "Mannix D.G."xsd:string |
http://purl.uniprot.org/citations/2524646 | http://purl.uniprot.org/core/date | "1989"xsd:gYear |
http://purl.uniprot.org/citations/2524646 | http://purl.uniprot.org/core/date | "1989"xsd:gYear |
http://purl.uniprot.org/citations/2524646 | http://purl.uniprot.org/core/name | "Mol. Cell. Biol."xsd:string |
http://purl.uniprot.org/citations/2524646 | http://purl.uniprot.org/core/name | "Mol. Cell. Biol."xsd:string |
http://purl.uniprot.org/citations/2524646 | http://purl.uniprot.org/core/pages | "1120-1127"xsd:string |
http://purl.uniprot.org/citations/2524646 | http://purl.uniprot.org/core/pages | "1120-1127"xsd:string |
http://purl.uniprot.org/citations/2524646 | http://purl.uniprot.org/core/title | "cys-3, the positive-acting sulfur regulatory gene of Neurospora crassa, encodes a protein with a putative leucine zipper DNA-binding element."xsd:string |
http://purl.uniprot.org/citations/2524646 | http://purl.uniprot.org/core/title | "cys-3, the positive-acting sulfur regulatory gene of Neurospora crassa, encodes a protein with a putative leucine zipper DNA-binding element."xsd:string |
http://purl.uniprot.org/citations/2524646 | http://purl.uniprot.org/core/volume | "9"xsd:string |
http://purl.uniprot.org/citations/2524646 | http://purl.uniprot.org/core/volume | "9"xsd:string |
http://purl.uniprot.org/citations/2524646 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/2524646 |
http://purl.uniprot.org/citations/2524646 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/2524646 |