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http://purl.uniprot.org/citations/2525380http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/2525380http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/2525380http://www.w3.org/2000/01/rdf-schema#comment"Using a specific radioimmunoassay we have isolated and sequenced a new 45-amino acid peptide from rat atria which exhibits similar physiological and pharmacological properties to rat atrial natriuretic peptide (rANP). We have termed the new peptide iso-rANP, because of its functional and structural similarities to rANP. Amino acid sequence differences show that iso-rANP is genetically distinct from rANP. Iso-rANP has a single disulfide bond between residues 23-39 and this portion of the peptide shows substantial homology to rANP and to porcine brain natriuretic peptide (BNP). Little homology is evident at the N- and C-termini of iso-rANP and ANP. Iso-rANP is equipotent with rANP in eliciting diuresis, natriuresis and hypotension in the bioassay rat."xsd:string
http://purl.uniprot.org/citations/2525380http://purl.org/dc/terms/identifier"doi:10.1016/0006-291x(89)92675-2"xsd:string
http://purl.uniprot.org/citations/2525380http://purl.org/dc/terms/identifier"doi:10.1016/0006-291x(89)92675-2"xsd:string
http://purl.uniprot.org/citations/2525380http://purl.uniprot.org/core/author"Tremblay L."xsd:string
http://purl.uniprot.org/citations/2525380http://purl.uniprot.org/core/author"Tremblay L."xsd:string
http://purl.uniprot.org/citations/2525380http://purl.uniprot.org/core/author"Flynn T.G."xsd:string
http://purl.uniprot.org/citations/2525380http://purl.uniprot.org/core/author"Flynn T.G."xsd:string
http://purl.uniprot.org/citations/2525380http://purl.uniprot.org/core/author"Lyons C."xsd:string
http://purl.uniprot.org/citations/2525380http://purl.uniprot.org/core/author"Lyons C."xsd:string
http://purl.uniprot.org/citations/2525380http://purl.uniprot.org/core/author"Brar A."xsd:string
http://purl.uniprot.org/citations/2525380http://purl.uniprot.org/core/author"Brar A."xsd:string
http://purl.uniprot.org/citations/2525380http://purl.uniprot.org/core/author"Jennings D.B."xsd:string
http://purl.uniprot.org/citations/2525380http://purl.uniprot.org/core/author"Jennings D.B."xsd:string
http://purl.uniprot.org/citations/2525380http://purl.uniprot.org/core/author"Sarda I."xsd:string
http://purl.uniprot.org/citations/2525380http://purl.uniprot.org/core/author"Sarda I."xsd:string
http://purl.uniprot.org/citations/2525380http://purl.uniprot.org/core/date"1989"xsd:gYear
http://purl.uniprot.org/citations/2525380http://purl.uniprot.org/core/date"1989"xsd:gYear
http://purl.uniprot.org/citations/2525380http://purl.uniprot.org/core/name"Biochem. Biophys. Res. Commun."xsd:string
http://purl.uniprot.org/citations/2525380http://purl.uniprot.org/core/name"Biochem. Biophys. Res. Commun."xsd:string
http://purl.uniprot.org/citations/2525380http://purl.uniprot.org/core/pages"830-837"xsd:string
http://purl.uniprot.org/citations/2525380http://purl.uniprot.org/core/pages"830-837"xsd:string
http://purl.uniprot.org/citations/2525380http://purl.uniprot.org/core/title"Isolation and characterization of iso-rANP, a new natriuretic peptide from rat atria."xsd:string
http://purl.uniprot.org/citations/2525380http://purl.uniprot.org/core/title"Isolation and characterization of iso-rANP, a new natriuretic peptide from rat atria."xsd:string