DESCRIBE <http://purl.uniprot.org/citations/25266175>

Subject	Predicate	Object
http://purl.uniprot.org/citations/25266175	http://www.w3.org/1999/02/22-rdf-syntax-ns#type	http://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/25266175	http://www.w3.org/2000/01/rdf-schema#comment	" Background Coronary anomalies are frequently associated with congenital cardiac defects. Accordingly, we tested the hypothesis that the development of the tunica media of coronary arteries/arterioles is compromised in mice with cardiac defects of the outflow tract (persistent truncus arteriosus, double outlet right ventricle and transposition of the great arteries) by studying hearts of G7-9 generation mice bred from mutagenized mice caused by N-ethyl-N-nitrosourea. Mice were studied at embryonic days E16.5, E17.5, and postnatal days 1 and 11. Data were based on immunohistochemistry of serial sections. Results In 21 of 24 mice with outflow tract defects, the development of smooth muscle in arteries and arterioles was retarded; most commonly arterioles had an incomplete layer of smooth muscle or in a few instances, lacked a tunica media. In this model, an absence of a coronary ostium occurred in only 2 mice, indicating that the mechanisms underlying the formation of coronary ostia and the recruitment and differentiation of vascular smooth muscle differ. Coronary fistulas were present in 20% and dilated vessels in 30% of the hearts with cardiac defects. Conclusions The data suggest that vascular smooth muscle recruitment and differentiation are not necessarily linked to other coronary anomalies, such as absence of a main coronary artery or branching patterns."xsd:string
http://purl.uniprot.org/citations/25266175	http://purl.org/dc/terms/identifier	"doi:10.1002/ar.23056"xsd:string
http://purl.uniprot.org/citations/25266175	http://purl.uniprot.org/core/author	"Yu Q."xsd:string
http://purl.uniprot.org/citations/25266175	http://purl.uniprot.org/core/author	"Lo C.W."xsd:string
http://purl.uniprot.org/citations/25266175	http://purl.uniprot.org/core/author	"Tomanek R.J."xsd:string
http://purl.uniprot.org/citations/25266175	http://purl.uniprot.org/core/date	"2015"xsd:gYear
http://purl.uniprot.org/citations/25266175	http://purl.uniprot.org/core/name	"Anat Rec (Hoboken)"xsd:string
http://purl.uniprot.org/citations/25266175	http://purl.uniprot.org/core/pages	"408-417"xsd:string
http://purl.uniprot.org/citations/25266175	http://purl.uniprot.org/core/title	"Coronary anomalies in mice with congenital heart defects."xsd:string
http://purl.uniprot.org/citations/25266175	http://purl.uniprot.org/core/volume	"298"xsd:string
http://purl.uniprot.org/citations/25266175	http://www.w3.org/2004/02/skos/core#exactMatch	http://purl.uniprot.org/pubmed/25266175
http://purl.uniprot.org/citations/25266175	http://xmlns.com/foaf/0.1/primaryTopicOf	https://pubmed.ncbi.nlm.nih.gov/25266175
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http://purl.uniprot.org/uniprot/#_P70658-mappedCitation-25266175	http://www.w3.org/1999/02/22-rdf-syntax-ns#object	http://purl.uniprot.org/citations/25266175
http://purl.uniprot.org/uniprot/#_A1E2I3-mappedCitation-25266175	http://www.w3.org/1999/02/22-rdf-syntax-ns#object	http://purl.uniprot.org/citations/25266175
http://purl.uniprot.org/uniprot/#_E9Q2D4-mappedCitation-25266175	http://www.w3.org/1999/02/22-rdf-syntax-ns#object	http://purl.uniprot.org/citations/25266175
http://purl.uniprot.org/uniprot/#_O35643-mappedCitation-25266175	http://www.w3.org/1999/02/22-rdf-syntax-ns#object	http://purl.uniprot.org/citations/25266175
http://purl.uniprot.org/uniprot/#_Q5SVG4-mappedCitation-25266175	http://www.w3.org/1999/02/22-rdf-syntax-ns#object	http://purl.uniprot.org/citations/25266175
http://purl.uniprot.org/uniprot/#_Q5SVG5-mappedCitation-25266175	http://www.w3.org/1999/02/22-rdf-syntax-ns#object	http://purl.uniprot.org/citations/25266175
http://purl.uniprot.org/uniprot/#_Q3TVN4-mappedCitation-25266175	http://www.w3.org/1999/02/22-rdf-syntax-ns#object	http://purl.uniprot.org/citations/25266175
http://purl.uniprot.org/uniprot/#_Q3U1K9-mappedCitation-25266175	http://www.w3.org/1999/02/22-rdf-syntax-ns#object	http://purl.uniprot.org/citations/25266175
http://purl.uniprot.org/uniprot/#_Q8CC13-mappedCitation-25266175	http://www.w3.org/1999/02/22-rdf-syntax-ns#object	http://purl.uniprot.org/citations/25266175
http://purl.uniprot.org/uniprot/#_Q6NXY3-mappedCitation-25266175	http://www.w3.org/1999/02/22-rdf-syntax-ns#object	http://purl.uniprot.org/citations/25266175
http://purl.uniprot.org/uniprot/P70658	http://purl.uniprot.org/core/mappedCitation	http://purl.uniprot.org/citations/25266175