| http://purl.uniprot.org/citations/25267411 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/25267411 | http://www.w3.org/2000/01/rdf-schema#comment | "Recently, we reported the properties of CD31-expressing cells in healthy individuals. However, the characteristics of CD31-expressing cells derived from coronary artery disease (CAD) patients remain unknown. This study aimed to investigate the relationship between circulating CD31(+) cells and CAD as well as their biological characteristics. Analysis with flow cytometry revealed that CD31(+) cells (C-CD31) from the peripheral blood (PB) of CAD patients exhibited low levels of T-cell marker and high levels of macrophage marker compared with the PB-CD31(+) cells from healthy individuals (H-CD31). In addition, the expression levels of multiple pro-angiogenic and chemokine genes were significantly down-regulated in C-CD31. However, inflammatory gene IL-1α was highly up-regulated in C-CD31. Patients with unstable angina (UA) had significantly more CD31(+) cells in the PB than healthy control group (P < 0.001). Moreover, there were significant correlations between the number of CD31(+) cells and cardiovascular (CV) disease activity (R = 0.318, P = 0.006) and the number of diseased coronaries (R = 0.312, P = 0.005). For the diagnostic category of UA, the area under curve was 0.803 (P < 0.001). In conclusion, C-CD31 have impaired angiogenic potential and the number of circulating CD31(+) cells were correlated with CV risk. These findings may contribute to the understanding of the pathogenesis of CAD."xsd:string |
| http://purl.uniprot.org/citations/25267411 | http://purl.org/dc/terms/identifier | "doi:10.1111/jcmm.12370"xsd:string |
| http://purl.uniprot.org/citations/25267411 | http://purl.uniprot.org/core/author | "Guo L."xsd:string |
| http://purl.uniprot.org/citations/25267411 | http://purl.uniprot.org/core/author | "Kim H.S."xsd:string |
| http://purl.uniprot.org/citations/25267411 | http://purl.uniprot.org/core/author | "Kim S.W."xsd:string |
| http://purl.uniprot.org/citations/25267411 | http://purl.uniprot.org/core/author | "Kim M.H."xsd:string |
| http://purl.uniprot.org/citations/25267411 | http://purl.uniprot.org/core/date | "2014"xsd:gYear |
| http://purl.uniprot.org/citations/25267411 | http://purl.uniprot.org/core/name | "J Cell Mol Med"xsd:string |
| http://purl.uniprot.org/citations/25267411 | http://purl.uniprot.org/core/pages | "2321-2330"xsd:string |
| http://purl.uniprot.org/citations/25267411 | http://purl.uniprot.org/core/title | "Characteristics of circulating CD31(+) cells from patients with coronary artery disease."xsd:string |
| http://purl.uniprot.org/citations/25267411 | http://purl.uniprot.org/core/volume | "18"xsd:string |
| http://purl.uniprot.org/citations/25267411 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/25267411 |
| http://purl.uniprot.org/citations/25267411 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/25267411 |
| http://purl.uniprot.org/uniprot/#_B7Z8U8-mappedCitation-25267411 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/25267411 |
| http://purl.uniprot.org/uniprot/#_B7Z8Y6-mappedCitation-25267411 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/25267411 |
| http://purl.uniprot.org/uniprot/#_P16284-mappedCitation-25267411 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/25267411 |
| http://purl.uniprot.org/uniprot/B7Z8U8 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/25267411 |
| http://purl.uniprot.org/uniprot/B7Z8Y6 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/25267411 |
| http://purl.uniprot.org/uniprot/P16284 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/25267411 |