| http://purl.uniprot.org/citations/2531008 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/2531008 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/2531008 | http://www.w3.org/2000/01/rdf-schema#comment | "The high-affinity cellular receptor for the basement membrane component laminin is differentially expressed during tumor invasion and metastasis. A cDNA clone encoding the murine laminin receptor was isolated and identified on the basis of sequence homology to the human laminin receptor [Wewer et al. (1986) Proc. Natl. Acad. Sci. U.S.A. 83, 7137-7141]. Primer extension experiments demonstrated that the clone contained the complete 5' sequence of the murine laminin receptor mRNA. RNA blot data demonstrated a single-sized laminin receptor mRNA, approximately 1400 bases long, in human, mouse, and rat. The nascent laminin receptor predicted from the cDNA sequence is 295 amino acids long, with a molecular weight of 33,000, and contains one intradisulfide bridge, a short putative transmembrane domain, and an extracellular carboxy-terminal region which has abundant glutamic acid residues and multiple repeat sequences. The precursor of the laminin receptor is apparently smaller than the 67-kilodalton protein isolated from tissue. The apparent molecular weight on SDS-polyacrylamide gels of the rabbit reticulocyte cell-free translation product of selectively hybridized laminin receptor mRNA is 37,000. Antisera to three different domains of the cDNA-predicted receptor were used to study the relationship between the 37- and 67-kilodalton polypeptides. Antisera to cDNA-deduced synthetic peptides of the receptor immunoprecipitated a 37-kilodalton band both from cell-free translation products and from pulse-labeled cell extracts. On immunoblots of cell extracts, one antisynthetic peptide antiserum recognized only the 67-kilodalton receptor, while another antiserum identified both 37- and 67-kilodalton polypeptides, suggesting a precursor-product relationship between the two polypeptides."xsd:string |
| http://purl.uniprot.org/citations/2531008 | http://purl.uniprot.org/core/name | "Biochemistry"xsd:string |
| http://purl.uniprot.org/citations/2531008 | http://purl.uniprot.org/core/name | "Biochemistry"xsd:string |
| http://purl.uniprot.org/citations/2531008 | http://purl.org/dc/terms/identifier | "doi:10.1021/bi00444a047"xsd:string |
| http://purl.uniprot.org/citations/2531008 | http://purl.org/dc/terms/identifier | "doi:10.1021/bi00444a047"xsd:string |
| http://purl.uniprot.org/citations/2531008 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/2531008 |
| http://purl.uniprot.org/citations/2531008 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/2531008 |
| http://purl.uniprot.org/citations/2531008 | http://purl.uniprot.org/core/author | "Wewer U.M."xsd:string |
| http://purl.uniprot.org/citations/2531008 | http://purl.uniprot.org/core/author | "Wewer U.M."xsd:string |
| http://purl.uniprot.org/citations/2531008 | http://purl.uniprot.org/core/author | "Rao C.N."xsd:string |
| http://purl.uniprot.org/citations/2531008 | http://purl.uniprot.org/core/author | "Rao C.N."xsd:string |
| http://purl.uniprot.org/citations/2531008 | http://purl.uniprot.org/core/author | "Liotta L.A."xsd:string |
| http://purl.uniprot.org/citations/2531008 | http://purl.uniprot.org/core/author | "Liotta L.A."xsd:string |
| http://purl.uniprot.org/citations/2531008 | http://purl.uniprot.org/core/author | "Castronovo V."xsd:string |
| http://purl.uniprot.org/citations/2531008 | http://purl.uniprot.org/core/author | "Castronovo V."xsd:string |
| http://purl.uniprot.org/citations/2531008 | http://purl.uniprot.org/core/author | "Sobel M.E."xsd:string |
| http://purl.uniprot.org/citations/2531008 | http://purl.uniprot.org/core/author | "Sobel M.E."xsd:string |
| http://purl.uniprot.org/citations/2531008 | http://purl.uniprot.org/core/author | "Schmitt M.C."xsd:string |
| http://purl.uniprot.org/citations/2531008 | http://purl.uniprot.org/core/author | "Schmitt M.C."xsd:string |
| http://purl.uniprot.org/citations/2531008 | http://purl.uniprot.org/core/author | "Claysmith A.P."xsd:string |
| http://purl.uniprot.org/citations/2531008 | http://purl.uniprot.org/core/author | "Claysmith A.P."xsd:string |
| http://purl.uniprot.org/citations/2531008 | http://purl.uniprot.org/core/date | "1989"xsd:gYear |
| http://purl.uniprot.org/citations/2531008 | http://purl.uniprot.org/core/date | "1989"xsd:gYear |