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http://purl.uniprot.org/citations/25373777http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/25373777http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/25373777http://www.w3.org/2000/01/rdf-schema#comment"Members of the Wnt family of secreted signaling proteins are key regulators of cell migration and axon guidance. In the nematode C. elegans, the migration of the QR neuroblast descendants requires multiple Wnt ligands and receptors. We found that the migration of the QR descendants is divided into three sequential phases that are each mediated by a distinct Wnt signaling mechanism. Importantly, the transition from the first to the second phase, which is the main determinant of the final position of the QR descendants along the anteroposterior body axis, is mediated through a cell-autonomous process in which the time-dependent expression of a Wnt receptor turns on the canonical Wnt/β-catenin signaling response that is required to terminate long-range anterior migration. Our results show that, in addition to direct guidance of cell migration by Wnt morphogenic gradients, cell migration can also be controlled indirectly through cell-intrinsic modulation of Wnt signaling responses."xsd:string
http://purl.uniprot.org/citations/25373777http://purl.org/dc/terms/identifier"doi:10.1016/j.devcel.2014.08.008"xsd:string
http://purl.uniprot.org/citations/25373777http://purl.org/dc/terms/identifier"doi:10.1016/j.devcel.2014.08.008"xsd:string
http://purl.uniprot.org/citations/25373777http://purl.uniprot.org/core/author"Betist M.C."xsd:string
http://purl.uniprot.org/citations/25373777http://purl.uniprot.org/core/author"Betist M.C."xsd:string
http://purl.uniprot.org/citations/25373777http://purl.uniprot.org/core/author"Korswagen H.C."xsd:string
http://purl.uniprot.org/citations/25373777http://purl.uniprot.org/core/author"Korswagen H.C."xsd:string
http://purl.uniprot.org/citations/25373777http://purl.uniprot.org/core/author"van Oudenaarden A."xsd:string
http://purl.uniprot.org/citations/25373777http://purl.uniprot.org/core/author"van Oudenaarden A."xsd:string
http://purl.uniprot.org/citations/25373777http://purl.uniprot.org/core/author"Ji N."xsd:string
http://purl.uniprot.org/citations/25373777http://purl.uniprot.org/core/author"Ji N."xsd:string
http://purl.uniprot.org/citations/25373777http://purl.uniprot.org/core/author"Mentink R.A."xsd:string
http://purl.uniprot.org/citations/25373777http://purl.uniprot.org/core/author"Mentink R.A."xsd:string
http://purl.uniprot.org/citations/25373777http://purl.uniprot.org/core/author"Middelkoop T.C."xsd:string
http://purl.uniprot.org/citations/25373777http://purl.uniprot.org/core/author"Middelkoop T.C."xsd:string
http://purl.uniprot.org/citations/25373777http://purl.uniprot.org/core/author"Rella L."xsd:string
http://purl.uniprot.org/citations/25373777http://purl.uniprot.org/core/author"Rella L."xsd:string
http://purl.uniprot.org/citations/25373777http://purl.uniprot.org/core/author"Tang C.Y."xsd:string
http://purl.uniprot.org/citations/25373777http://purl.uniprot.org/core/author"Tang C.Y."xsd:string
http://purl.uniprot.org/citations/25373777http://purl.uniprot.org/core/date"2014"xsd:gYear
http://purl.uniprot.org/citations/25373777http://purl.uniprot.org/core/date"2014"xsd:gYear
http://purl.uniprot.org/citations/25373777http://purl.uniprot.org/core/name"Dev. Cell"xsd:string
http://purl.uniprot.org/citations/25373777http://purl.uniprot.org/core/name"Dev. Cell"xsd:string