http://purl.uniprot.org/citations/25378285 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/25378285 | http://www.w3.org/2000/01/rdf-schema#comment | "This study has investigated the patterns of colocalisation of the conventional K cell marker, glucagon-like insulinotropic peptide (GIP), and the L cell markers, glucagon like peptide-1 (GLP-1) and peptide YY (PYY), in enteroendocrine cells (EEC) of the small intestine and colon of mouse and pig. All combinations of the hormones, 3 in a cell, 2 in a cell and 1 at a time, were encountered. In both species, the three most common EEC types contained (1) both GLP-1 and PYY but not GIP, (2) GLP-1 alone or (3) GIP plus GLP-1 without PYY. Few GIP plus PYY cells and rare cells containing all 3 hormones were encountered. Gradients of cell types occurred along the intestine. For example, in mouse, there were no PYY cells in the duodenum and few in the jejunum, but >50% of labelled EEC in the distal ileum and colon were PYY immunoreactive. By contrast, over 40% of EEC in the pig duodenum contained PYY, and most also contained either GLP-1 or GIP. The gradient in pig was less pronounced. It is concluded that the traditional classification of K and L cells requires revision, and that there are major inter-species differences in the patterns of colocalisation of hormones that have been used to characterise K and L cells."xsd:string |
http://purl.uniprot.org/citations/25378285 | http://purl.org/dc/terms/identifier | "doi:10.1007/s00441-014-2033-3"xsd:string |
http://purl.uniprot.org/citations/25378285 | http://purl.uniprot.org/core/author | "Cho H.J."xsd:string |
http://purl.uniprot.org/citations/25378285 | http://purl.uniprot.org/core/author | "Callaghan B."xsd:string |
http://purl.uniprot.org/citations/25378285 | http://purl.uniprot.org/core/author | "Furness J.B."xsd:string |
http://purl.uniprot.org/citations/25378285 | http://purl.uniprot.org/core/author | "Bravo D.M."xsd:string |
http://purl.uniprot.org/citations/25378285 | http://purl.uniprot.org/core/author | "Hunne B."xsd:string |
http://purl.uniprot.org/citations/25378285 | http://purl.uniprot.org/core/author | "Rivera L.R."xsd:string |
http://purl.uniprot.org/citations/25378285 | http://purl.uniprot.org/core/author | "Kosari S."xsd:string |
http://purl.uniprot.org/citations/25378285 | http://purl.uniprot.org/core/date | "2015"xsd:gYear |
http://purl.uniprot.org/citations/25378285 | http://purl.uniprot.org/core/name | "Cell Tissue Res"xsd:string |
http://purl.uniprot.org/citations/25378285 | http://purl.uniprot.org/core/pages | "693-698"xsd:string |
http://purl.uniprot.org/citations/25378285 | http://purl.uniprot.org/core/title | "Differences in hormone localisation patterns of K and L type enteroendocrine cells in the mouse and pig small intestine and colon."xsd:string |
http://purl.uniprot.org/citations/25378285 | http://purl.uniprot.org/core/volume | "359"xsd:string |
http://purl.uniprot.org/citations/25378285 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/25378285 |
http://purl.uniprot.org/citations/25378285 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/25378285 |
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