| http://purl.uniprot.org/citations/25378482 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/25378482 | http://www.w3.org/2000/01/rdf-schema#comment | "Intrinsic Notch signaling in intestinal epithelial cells restricts secretory cell differentiation. In gut-associated lymphoid tissue (GALT), stromal cells located beneath the follicle-associated epithelium (FAE) abundantly express the Notch ligand delta-like 1 (Dll1). Here, we show that mice lacking Rbpj-a gene encoding a transcription factor implicated in Notch signaling-in intestinal epithelial cells have defective GALT maturation. This defect can be attributed to the expansion of goblet cells, which leads to the down-regulation of CCL20 in FAE. These data demonstrate that epithelial Notch signaling maintained by stromal cells contributes to the full maturation of GALT by restricting secretory cell differentiation in FAE."xsd:string |
| http://purl.uniprot.org/citations/25378482 | http://purl.org/dc/terms/identifier | "doi:10.15252/embr.201438942"xsd:string |
| http://purl.uniprot.org/citations/25378482 | http://purl.uniprot.org/core/author | "Ebisawa M."xsd:string |
| http://purl.uniprot.org/citations/25378482 | http://purl.uniprot.org/core/author | "Kimura S."xsd:string |
| http://purl.uniprot.org/citations/25378482 | http://purl.uniprot.org/core/author | "Nakamura Y."xsd:string |
| http://purl.uniprot.org/citations/25378482 | http://purl.uniprot.org/core/author | "Ohno H."xsd:string |
| http://purl.uniprot.org/citations/25378482 | http://purl.uniprot.org/core/author | "Suzuki K."xsd:string |
| http://purl.uniprot.org/citations/25378482 | http://purl.uniprot.org/core/author | "Yoshida H."xsd:string |
| http://purl.uniprot.org/citations/25378482 | http://purl.uniprot.org/core/author | "Sugiyama M."xsd:string |
| http://purl.uniprot.org/citations/25378482 | http://purl.uniprot.org/core/author | "Hase K."xsd:string |
| http://purl.uniprot.org/citations/25378482 | http://purl.uniprot.org/core/author | "Iwanaga T."xsd:string |
| http://purl.uniprot.org/citations/25378482 | http://purl.uniprot.org/core/author | "Miyagawa Y."xsd:string |
| http://purl.uniprot.org/citations/25378482 | http://purl.uniprot.org/core/author | "Furusawa Y."xsd:string |
| http://purl.uniprot.org/citations/25378482 | http://purl.uniprot.org/core/author | "Obata Y."xsd:string |
| http://purl.uniprot.org/citations/25378482 | http://purl.uniprot.org/core/author | "Fujimura Y."xsd:string |
| http://purl.uniprot.org/citations/25378482 | http://purl.uniprot.org/core/author | "Nakato G."xsd:string |
| http://purl.uniprot.org/citations/25378482 | http://purl.uniprot.org/core/author | "Iizuka K."xsd:string |
| http://purl.uniprot.org/citations/25378482 | http://purl.uniprot.org/core/date | "2014"xsd:gYear |
| http://purl.uniprot.org/citations/25378482 | http://purl.uniprot.org/core/name | "EMBO Rep"xsd:string |
| http://purl.uniprot.org/citations/25378482 | http://purl.uniprot.org/core/pages | "1297-1304"xsd:string |
| http://purl.uniprot.org/citations/25378482 | http://purl.uniprot.org/core/title | "Epithelial-stromal interaction via Notch signaling is essential for the full maturation of gut-associated lymphoid tissues."xsd:string |
| http://purl.uniprot.org/citations/25378482 | http://purl.uniprot.org/core/volume | "15"xsd:string |
| http://purl.uniprot.org/citations/25378482 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/25378482 |
| http://purl.uniprot.org/citations/25378482 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/25378482 |