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http://purl.uniprot.org/citations/25400923http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/25400923http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/25400923http://www.w3.org/2000/01/rdf-schema#comment"BEN domain-containing protein 3 (BEND3) has no transmembrane region, is localized in the cytoplasm, and is involved in chromatin function and transcription. We here identified a novel subpopulation of human T cells that expressed BEND3 on their cell surface (BEND3(+) T cells). BEND3(+) T cells consisted of approximately 3% of T cells in the peripheral blood, were present in both CD4(+) and CD8(+) T cells, and were also observed in cord blood. The stimulation of BEND3(+) T cells through the TCR/CD3 complex led to the production of various kinds of cytokines; however, the levels of IL-6 and IL-8 produced by BEND3(+) T cells were higher than those by BEND3(-) T cells. The proportion of BEND3(+) T cells was also increased in some patients with inflammatory diseases. Taken together, these results indicate that BEND3(+) T cells are a new subpopulation of T cells in terms of their cytokine profile. Further analyses on BEND3(+) T cells may be of importance and useful in understanding human T cell immunology."xsd:string
http://purl.uniprot.org/citations/25400923http://purl.org/dc/terms/identifier"doi:10.1002/iid3.17"xsd:string
http://purl.uniprot.org/citations/25400923http://purl.org/dc/terms/identifier"doi:10.1002/iid3.17"xsd:string
http://purl.uniprot.org/citations/25400923http://purl.uniprot.org/core/author"Oku T."xsd:string
http://purl.uniprot.org/citations/25400923http://purl.uniprot.org/core/author"Oku T."xsd:string
http://purl.uniprot.org/citations/25400923http://purl.uniprot.org/core/author"Kobayashi S."xsd:string
http://purl.uniprot.org/citations/25400923http://purl.uniprot.org/core/author"Kobayashi S."xsd:string
http://purl.uniprot.org/citations/25400923http://purl.uniprot.org/core/author"Watanabe T."xsd:string
http://purl.uniprot.org/citations/25400923http://purl.uniprot.org/core/author"Watanabe T."xsd:string
http://purl.uniprot.org/citations/25400923http://purl.uniprot.org/core/author"Sasaki C."xsd:string
http://purl.uniprot.org/citations/25400923http://purl.uniprot.org/core/author"Sasaki C."xsd:string
http://purl.uniprot.org/citations/25400923http://purl.uniprot.org/core/author"Hikida M."xsd:string
http://purl.uniprot.org/citations/25400923http://purl.uniprot.org/core/author"Hikida M."xsd:string
http://purl.uniprot.org/citations/25400923http://purl.uniprot.org/core/author"Hirayama Y."xsd:string
http://purl.uniprot.org/citations/25400923http://purl.uniprot.org/core/author"Hirayama Y."xsd:string
http://purl.uniprot.org/citations/25400923http://purl.uniprot.org/core/author"Aoyama T."xsd:string
http://purl.uniprot.org/citations/25400923http://purl.uniprot.org/core/author"Aoyama T."xsd:string
http://purl.uniprot.org/citations/25400923http://purl.uniprot.org/core/author"Shimizu J."xsd:string
http://purl.uniprot.org/citations/25400923http://purl.uniprot.org/core/author"Shimizu J."xsd:string
http://purl.uniprot.org/citations/25400923http://purl.uniprot.org/core/author"Mimori T."xsd:string
http://purl.uniprot.org/citations/25400923http://purl.uniprot.org/core/author"Mimori T."xsd:string
http://purl.uniprot.org/citations/25400923http://purl.uniprot.org/core/author"Kitagori K."xsd:string
http://purl.uniprot.org/citations/25400923http://purl.uniprot.org/core/author"Kitagori K."xsd:string