http://purl.uniprot.org/citations/25413675 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/25413675 | http://www.w3.org/2000/01/rdf-schema#comment | "Tissues use numerous mechanisms to change shape during development. The Drosophila egg chamber is an organ-like structure that elongates to form an elliptical egg. During elongation the follicular epithelial cells undergo a collective migration that causes the egg chamber to rotate within its surrounding basement membrane. Rotation coincides with the formation of a 'molecular corset', in which actin bundles in the epithelium and fibrils in the basement membrane are all aligned perpendicular to the elongation axis. Here we show that rotation plays a critical role in building the actin-based component of the corset. Rotation begins shortly after egg chamber formation and requires lamellipodial protrusions at each follicle cell's leading edge. During early stages, rotation is necessary for tissue-level actin bundle alignment, but it becomes dispensable after the basement membrane is polarized. This work highlights how collective cell migration can be used to build a polarized tissue organization for organ morphogenesis."xsd:string |
http://purl.uniprot.org/citations/25413675 | http://purl.org/dc/terms/identifier | "doi:10.1038/ncomms6511"xsd:string |
http://purl.uniprot.org/citations/25413675 | http://purl.uniprot.org/core/author | "Lewellyn L."xsd:string |
http://purl.uniprot.org/citations/25413675 | http://purl.uniprot.org/core/author | "Horne-Badovinac S."xsd:string |
http://purl.uniprot.org/citations/25413675 | http://purl.uniprot.org/core/author | "Tanentzapf G."xsd:string |
http://purl.uniprot.org/citations/25413675 | http://purl.uniprot.org/core/author | "Fairchild M.J."xsd:string |
http://purl.uniprot.org/citations/25413675 | http://purl.uniprot.org/core/author | "Gardel M.L."xsd:string |
http://purl.uniprot.org/citations/25413675 | http://purl.uniprot.org/core/author | "Oakes P.W."xsd:string |
http://purl.uniprot.org/citations/25413675 | http://purl.uniprot.org/core/author | "Cetera M."xsd:string |
http://purl.uniprot.org/citations/25413675 | http://purl.uniprot.org/core/author | "Ramirez-San Juan G.R."xsd:string |
http://purl.uniprot.org/citations/25413675 | http://purl.uniprot.org/core/date | "2014"xsd:gYear |
http://purl.uniprot.org/citations/25413675 | http://purl.uniprot.org/core/name | "Nat Commun"xsd:string |
http://purl.uniprot.org/citations/25413675 | http://purl.uniprot.org/core/pages | "5511"xsd:string |
http://purl.uniprot.org/citations/25413675 | http://purl.uniprot.org/core/title | "Epithelial rotation promotes the global alignment of contractile actin bundles during Drosophila egg chamber elongation."xsd:string |
http://purl.uniprot.org/citations/25413675 | http://purl.uniprot.org/core/volume | "5"xsd:string |
http://purl.uniprot.org/citations/25413675 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/25413675 |
http://purl.uniprot.org/citations/25413675 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/25413675 |
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http://purl.uniprot.org/uniprot/#_A0A0B4K774-mappedCitation-25413675 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/25413675 |
http://purl.uniprot.org/uniprot/#_A0A0B4LFX0-mappedCitation-25413675 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/25413675 |
http://purl.uniprot.org/uniprot/#_F6J1D0-mappedCitation-25413675 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/25413675 |
http://purl.uniprot.org/uniprot/#_M9NCT2-mappedCitation-25413675 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/25413675 |
http://purl.uniprot.org/uniprot/#_D3DMM0-mappedCitation-25413675 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/25413675 |
http://purl.uniprot.org/uniprot/#_F2FB81-mappedCitation-25413675 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/25413675 |