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http://purl.uniprot.org/citations/25454626http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/25454626http://www.w3.org/2000/01/rdf-schema#comment"Psoriatic arthritis (PsA) is a complex genetic disorder that results from an interplay between multiple genetic and environmental factors. The aim of the study was to assess the significance of the association between the HLA-C and HLA-E allelic groups and PsA. Our results confirm the association between HLA-C(∗)06 and PsA (OR=5.16, p<0.0001). Furthermore, HLA-C(∗)06-positive patients develop more severe disease (p<0.01) and more frequently present with polyarticular pattern of PsA (p=0.08). Additionally our study revealed that the HLA-C(∗)02 allele was more frequently observed in PsA patients (OR=5.40, p<0.0005) and also that the HLA-E(∗)01:01 allele was significantly over-represented among HLA-C(∗)02-negative patients in comparison to healthy individuals (OR=6.44, p=0.045). Therefore these results suggest that the HLA-E and HLA-C(∗)02 molecules may also play an important role in determination immune response contributing to the PsA development."xsd:string
http://purl.uniprot.org/citations/25454626http://purl.org/dc/terms/identifier"doi:10.1016/j.humimm.2014.10.005"xsd:string
http://purl.uniprot.org/citations/25454626http://purl.uniprot.org/core/author"Bogunia-Kubik K."xsd:string
http://purl.uniprot.org/citations/25454626http://purl.uniprot.org/core/author"Wiland P."xsd:string
http://purl.uniprot.org/citations/25454626http://purl.uniprot.org/core/author"Gebura K."xsd:string
http://purl.uniprot.org/citations/25454626http://purl.uniprot.org/core/author"Korman L."xsd:string
http://purl.uniprot.org/citations/25454626http://purl.uniprot.org/core/author"Swierkot J."xsd:string
http://purl.uniprot.org/citations/25454626http://purl.uniprot.org/core/author"Iwaszko M."xsd:string
http://purl.uniprot.org/citations/25454626http://purl.uniprot.org/core/author"Sokolik R."xsd:string
http://purl.uniprot.org/citations/25454626http://purl.uniprot.org/core/date"2014"xsd:gYear
http://purl.uniprot.org/citations/25454626http://purl.uniprot.org/core/name"Hum Immunol"xsd:string
http://purl.uniprot.org/citations/25454626http://purl.uniprot.org/core/pages"1188-1191"xsd:string
http://purl.uniprot.org/citations/25454626http://purl.uniprot.org/core/title"Significance of association of HLA-C and HLA-E with psoriatic arthritis."xsd:string
http://purl.uniprot.org/citations/25454626http://purl.uniprot.org/core/volume"75"xsd:string
http://purl.uniprot.org/citations/25454626http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/25454626
http://purl.uniprot.org/citations/25454626http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/25454626
http://purl.uniprot.org/uniprot/#_A0A0A7C549-mappedCitation-25454626http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/25454626
http://purl.uniprot.org/uniprot/#_A0A0A7C553-mappedCitation-25454626http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/25454626
http://purl.uniprot.org/uniprot/#_A0A089N0V0-mappedCitation-25454626http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/25454626
http://purl.uniprot.org/uniprot/#_A0A0A7C850-mappedCitation-25454626http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/25454626
http://purl.uniprot.org/uniprot/#_A0A0A7C8P1-mappedCitation-25454626http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/25454626
http://purl.uniprot.org/uniprot/#_A0A0A7C8P4-mappedCitation-25454626http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/25454626
http://purl.uniprot.org/uniprot/#_A0A0A7C8P8-mappedCitation-25454626http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/25454626
http://purl.uniprot.org/uniprot/#_A0A0A7C8Q2-mappedCitation-25454626http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/25454626