| http://purl.uniprot.org/citations/25455425 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/25455425 | http://www.w3.org/2000/01/rdf-schema#comment | "As a variant of the Pavlovian fear conditioning paradigm the conditional discrimination design allows for a detailed investigation of fear acquisition and fear inhibition. Measuring fear-potentiated startle responses, we investigated the influence of two genetic polymorphisms (5-HTTLPR and COMT Val(158)Met) on fear acquisition and fear inhibition which are considered to be critical mechanisms for the etiology and maintenance of anxiety disorders. 5-HTTLPR s-allele carriers showed a more stable potentiation of the startle response during fear acquisition. Homozygous COMT Met-allele carriers, which had demonstrated delayed extinction in previous investigations, show deficient fear inhibition in presence of a learned safety signal. Thus, our results provide further evidence that 5-HTTLPR and COMT Val(158)Met genotypes influence the vulnerability for the development of anxiety disorders via different mechanisms."xsd:string |
| http://purl.uniprot.org/citations/25455425 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.ijpsycho.2014.10.007"xsd:string |
| http://purl.uniprot.org/citations/25455425 | http://purl.uniprot.org/core/author | "Wendt J."xsd:string |
| http://purl.uniprot.org/citations/25455425 | http://purl.uniprot.org/core/author | "Homuth G."xsd:string |
| http://purl.uniprot.org/citations/25455425 | http://purl.uniprot.org/core/author | "Lindner K."xsd:string |
| http://purl.uniprot.org/citations/25455425 | http://purl.uniprot.org/core/author | "Neubert J."xsd:string |
| http://purl.uniprot.org/citations/25455425 | http://purl.uniprot.org/core/author | "Ernst F.D."xsd:string |
| http://purl.uniprot.org/citations/25455425 | http://purl.uniprot.org/core/author | "Hamm A.O."xsd:string |
| http://purl.uniprot.org/citations/25455425 | http://purl.uniprot.org/core/author | "Weike A.I."xsd:string |
| http://purl.uniprot.org/citations/25455425 | http://purl.uniprot.org/core/date | "2015"xsd:gYear |
| http://purl.uniprot.org/citations/25455425 | http://purl.uniprot.org/core/name | "Int J Psychophysiol"xsd:string |
| http://purl.uniprot.org/citations/25455425 | http://purl.uniprot.org/core/pages | "499-505"xsd:string |
| http://purl.uniprot.org/citations/25455425 | http://purl.uniprot.org/core/title | "Genetic influences on the acquisition and inhibition of fear."xsd:string |
| http://purl.uniprot.org/citations/25455425 | http://purl.uniprot.org/core/volume | "98"xsd:string |
| http://purl.uniprot.org/citations/25455425 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/25455425 |
| http://purl.uniprot.org/citations/25455425 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/25455425 |
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