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http://purl.uniprot.org/citations/25467976http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/25467976http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/25467976http://www.w3.org/2000/01/rdf-schema#comment"Aminoacyl-tRNA synthetases (AminoARSs) are essential enzymes involved in acylating tRNA with amino acids. In addition to the typical functions of AminoARSs, various non-canonical functions have been reported, such as involvement in cellular regulatory processes and signal transduction. Here, to explore the cellular changes in sensory neurons after nerve injury, we evaluated AARS mRNA expression in rat dorsal root ganglia (DRG) neurons using AminoARS-specific primers. Of 20 AminoARSs, we found that expression of lysyl-tRNA synthetase (KARS) and glutaminyl-tRNA synthetase (QARS) was decreased in the DRG injured side. We observed decreased KARS and QARS expression in DRG neuronal cell bodies, but not in satellite cells. Therefore, we suggest the possibility that KARS and QARS may act as signaling molecules to transfer abnormal sensory signals to the spinal dorsal horn after peripheral nerve damage. Therefore, KARS and QARS may represent powerful pharmaceutical targets via control of their non-canonical functions."xsd:string
http://purl.uniprot.org/citations/25467976http://purl.org/dc/terms/identifier"doi:10.1007/s10735-014-9601-4"xsd:string
http://purl.uniprot.org/citations/25467976http://purl.org/dc/terms/identifier"doi:10.1007/s10735-014-9601-4"xsd:string
http://purl.uniprot.org/citations/25467976http://purl.uniprot.org/core/author"Jung J."xsd:string
http://purl.uniprot.org/citations/25467976http://purl.uniprot.org/core/author"Jung J."xsd:string
http://purl.uniprot.org/citations/25467976http://purl.uniprot.org/core/author"Park B.S."xsd:string
http://purl.uniprot.org/citations/25467976http://purl.uniprot.org/core/author"Park B.S."xsd:string
http://purl.uniprot.org/citations/25467976http://purl.uniprot.org/core/author"Jo H.W."xsd:string
http://purl.uniprot.org/citations/25467976http://purl.uniprot.org/core/author"Jo H.W."xsd:string
http://purl.uniprot.org/citations/25467976http://purl.uniprot.org/core/date"2015"xsd:gYear
http://purl.uniprot.org/citations/25467976http://purl.uniprot.org/core/date"2015"xsd:gYear
http://purl.uniprot.org/citations/25467976http://purl.uniprot.org/core/name"J. Mol. Histol."xsd:string
http://purl.uniprot.org/citations/25467976http://purl.uniprot.org/core/name"J. Mol. Histol."xsd:string
http://purl.uniprot.org/citations/25467976http://purl.uniprot.org/core/pages"115-122"xsd:string
http://purl.uniprot.org/citations/25467976http://purl.uniprot.org/core/pages"115-122"xsd:string
http://purl.uniprot.org/citations/25467976http://purl.uniprot.org/core/title"Expression profile of aminoacyl-tRNA synthetases in dorsal root ganglion neurons after peripheral nerve injury."xsd:string
http://purl.uniprot.org/citations/25467976http://purl.uniprot.org/core/title"Expression profile of aminoacyl-tRNA synthetases in dorsal root ganglion neurons after peripheral nerve injury."xsd:string
http://purl.uniprot.org/citations/25467976http://purl.uniprot.org/core/volume"46"xsd:string
http://purl.uniprot.org/citations/25467976http://purl.uniprot.org/core/volume"46"xsd:string
http://purl.uniprot.org/citations/25467976http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/25467976
http://purl.uniprot.org/citations/25467976http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/25467976
http://purl.uniprot.org/citations/25467976http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/25467976
http://purl.uniprot.org/citations/25467976http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/25467976