DESCRIBE <http://purl.uniprot.org/citations/25511212>

Subject	Predicate	Object
http://purl.uniprot.org/citations/25511212	http://www.w3.org/1999/02/22-rdf-syntax-ns#type	http://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/25511212	http://www.w3.org/2000/01/rdf-schema#comment	" Background Proliferation and differentiation of cancer cells are regulated by various cell cycle promoting and inhibiting factors. Our knowledge about these proteins and mechanisms regulating cell cycle progression has increased dramatically in recent years. Aim The present study was undertaken to examine the expression profile of cell cycle regulatory proteins in normal proliferative endometrium, hyperplasias (simple, complex and atypical) and endometrial carcinoma in a quantitative approach as also to assess correlations of Cyclin D1 expression with Ki-67 a proliferation marker. Settings and design A retrospective case control study in a tertiary referral centre. Materials and methods We evaluated and compared the expression profile of Cyclin D1 and Ki-67 expressions in 61 endometrial samples submitted as either endometrial curetting or hysterectomy specimens, which were diagnosed as simple hyperplasia (n=11), complex hyperplasia (n=13), atypical hyperplasia (n=7), and endometrial carcinoma (n=20). Results There was increased expression of Cyclin D1 and Ki-67 in patients with endometrial carcinoma relative to proliferative endometrium and simple hyperplasia, but there was no such difference between cases of atypical hyperplasia and endometrial carcinoma. Cyclin D1 expression had a positive correlation with Ki-67 expression. Cyclin D1 together with Ki-67 may be a marker for endometrial carcinogenesis and tumor cell proliferation."xsd:string
http://purl.uniprot.org/citations/25511212	http://purl.org/dc/terms/identifier	"doi:10.4103/0022-3859.147025"xsd:string
http://purl.uniprot.org/citations/25511212	http://purl.uniprot.org/core/author	"Ghosh A."xsd:string
http://purl.uniprot.org/citations/25511212	http://purl.uniprot.org/core/author	"Kumar M."xsd:string
http://purl.uniprot.org/citations/25511212	http://purl.uniprot.org/core/author	"Shevra C.R."xsd:string
http://purl.uniprot.org/citations/25511212	http://purl.uniprot.org/core/date	"2015"xsd:gYear
http://purl.uniprot.org/citations/25511212	http://purl.uniprot.org/core/name	"J Postgrad Med"xsd:string
http://purl.uniprot.org/citations/25511212	http://purl.uniprot.org/core/pages	"15-20"xsd:string
http://purl.uniprot.org/citations/25511212	http://purl.uniprot.org/core/title	"Cyclin D1 and Ki-67 expression in normal, hyperplastic and neoplastic endometrium."xsd:string
http://purl.uniprot.org/citations/25511212	http://purl.uniprot.org/core/volume	"61"xsd:string
http://purl.uniprot.org/citations/25511212	http://www.w3.org/2004/02/skos/core#exactMatch	http://purl.uniprot.org/pubmed/25511212
http://purl.uniprot.org/citations/25511212	http://xmlns.com/foaf/0.1/primaryTopicOf	https://pubmed.ncbi.nlm.nih.gov/25511212
http://purl.uniprot.org/uniprot/#_B4DRH3-mappedCitation-25511212	http://www.w3.org/1999/02/22-rdf-syntax-ns#object	http://purl.uniprot.org/citations/25511212
http://purl.uniprot.org/uniprot/#_B4DR06-mappedCitation-25511212	http://www.w3.org/1999/02/22-rdf-syntax-ns#object	http://purl.uniprot.org/citations/25511212
http://purl.uniprot.org/uniprot/#_Q14092-mappedCitation-25511212	http://www.w3.org/1999/02/22-rdf-syntax-ns#object	http://purl.uniprot.org/citations/25511212
http://purl.uniprot.org/uniprot/#_P24385-mappedCitation-25511212	http://www.w3.org/1999/02/22-rdf-syntax-ns#object	http://purl.uniprot.org/citations/25511212
http://purl.uniprot.org/uniprot/#_P46013-mappedCitation-25511212	http://www.w3.org/1999/02/22-rdf-syntax-ns#object	http://purl.uniprot.org/citations/25511212
http://purl.uniprot.org/uniprot/#_Q5MGB2-mappedCitation-25511212	http://www.w3.org/1999/02/22-rdf-syntax-ns#object	http://purl.uniprot.org/citations/25511212
http://purl.uniprot.org/uniprot/#_Q6FI00-mappedCitation-25511212	http://www.w3.org/1999/02/22-rdf-syntax-ns#object	http://purl.uniprot.org/citations/25511212
http://purl.uniprot.org/uniprot/#_Q70L72-mappedCitation-25511212	http://www.w3.org/1999/02/22-rdf-syntax-ns#object	http://purl.uniprot.org/citations/25511212
http://purl.uniprot.org/uniprot/#_Q70L73-mappedCitation-25511212	http://www.w3.org/1999/02/22-rdf-syntax-ns#object	http://purl.uniprot.org/citations/25511212
http://purl.uniprot.org/uniprot/#_Q70L74-mappedCitation-25511212	http://www.w3.org/1999/02/22-rdf-syntax-ns#object	http://purl.uniprot.org/citations/25511212
http://purl.uniprot.org/uniprot/P46013	http://purl.uniprot.org/core/mappedCitation	http://purl.uniprot.org/citations/25511212
http://purl.uniprot.org/uniprot/Q70L72	http://purl.uniprot.org/core/mappedCitation	http://purl.uniprot.org/citations/25511212