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http://purl.uniprot.org/citations/2553542http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/2553542http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/2553542http://www.w3.org/2000/01/rdf-schema#comment"Resistance to the aminoglycosides gentamicin, tobramycin and kanamycin (GmTmKmR) in Australian clinical strains of Staphylococcus aureus is commonly carried on the composite transposon Tn4001. The resistance gene aacA-aphD of Tn4001, which encodes a bifunctional AAC(6')-APH(2") modifying enzyme, is flanked by two 1324-bp inverted repeats, IS256L and IS256R, that are identical in sequence. Analysis of the IS256 sequence revealed structural features characteristic of IS elements including 26-bp imperfect terminal inverted repeats and a single open reading frame with coding capacity for a 45.6 kDa protein. The nucleotide sequence of IS256 described here, together with the sequence of the aacA-aphD gene reported previously [Rouch et al., J. Gen. Microbiol. 133 (1987) 3039-3052], completes the entire sequence of Tn4001, which totals 4566 bp."xsd:string
http://purl.uniprot.org/citations/2553542http://purl.org/dc/terms/identifier"doi:10.1016/0378-1119(89)90197-2"xsd:string
http://purl.uniprot.org/citations/2553542http://purl.org/dc/terms/identifier"doi:10.1016/0378-1119(89)90197-2"xsd:string
http://purl.uniprot.org/citations/2553542http://purl.uniprot.org/core/author"Byrne M.E."xsd:string
http://purl.uniprot.org/citations/2553542http://purl.uniprot.org/core/author"Byrne M.E."xsd:string
http://purl.uniprot.org/citations/2553542http://purl.uniprot.org/core/author"Rouch D.A."xsd:string
http://purl.uniprot.org/citations/2553542http://purl.uniprot.org/core/author"Rouch D.A."xsd:string
http://purl.uniprot.org/citations/2553542http://purl.uniprot.org/core/author"Skurray R.A."xsd:string
http://purl.uniprot.org/citations/2553542http://purl.uniprot.org/core/author"Skurray R.A."xsd:string
http://purl.uniprot.org/citations/2553542http://purl.uniprot.org/core/date"1989"xsd:gYear
http://purl.uniprot.org/citations/2553542http://purl.uniprot.org/core/date"1989"xsd:gYear
http://purl.uniprot.org/citations/2553542http://purl.uniprot.org/core/name"Gene"xsd:string
http://purl.uniprot.org/citations/2553542http://purl.uniprot.org/core/name"Gene"xsd:string
http://purl.uniprot.org/citations/2553542http://purl.uniprot.org/core/pages"361-367"xsd:string
http://purl.uniprot.org/citations/2553542http://purl.uniprot.org/core/pages"361-367"xsd:string
http://purl.uniprot.org/citations/2553542http://purl.uniprot.org/core/title"Nucleotide sequence analysis of IS256 from the Staphylococcus aureus gentamicin-tobramycin-kanamycin-resistance transposon Tn4001."xsd:string
http://purl.uniprot.org/citations/2553542http://purl.uniprot.org/core/title"Nucleotide sequence analysis of IS256 from the Staphylococcus aureus gentamicin-tobramycin-kanamycin-resistance transposon Tn4001."xsd:string
http://purl.uniprot.org/citations/2553542http://purl.uniprot.org/core/volume"81"xsd:string
http://purl.uniprot.org/citations/2553542http://purl.uniprot.org/core/volume"81"xsd:string
http://purl.uniprot.org/citations/2553542http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/2553542
http://purl.uniprot.org/citations/2553542http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/2553542
http://purl.uniprot.org/citations/2553542http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/2553542
http://purl.uniprot.org/citations/2553542http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/2553542