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http://purl.uniprot.org/citations/25581707http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/25581707http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/25581707http://www.w3.org/2000/01/rdf-schema#comment"The structures of the O-glycosyltransferase LanGT2 and the engineered, C-C bond-forming variant LanGT2S8Ac show how the replacement of a single loop can change the functionality of the enzyme. Crystal structures of the enzymes in complex with a nonhydrolyzable nucleotide-sugar analogue revealed that there is a conformational transition to create the binding sites for the aglycon substrate. This induced-fit transition was explored by molecular docking experiments with various aglycon substrates."xsd:string
http://purl.uniprot.org/citations/25581707http://purl.org/dc/terms/identifier"doi:10.1002/anie.201409792"xsd:string
http://purl.uniprot.org/citations/25581707http://purl.org/dc/terms/identifier"doi:10.1002/anie.201409792"xsd:string
http://purl.uniprot.org/citations/25581707http://purl.uniprot.org/core/author"Einsle O."xsd:string
http://purl.uniprot.org/citations/25581707http://purl.uniprot.org/core/author"Einsle O."xsd:string
http://purl.uniprot.org/citations/25581707http://purl.uniprot.org/core/author"Wang G."xsd:string
http://purl.uniprot.org/citations/25581707http://purl.uniprot.org/core/author"Wang G."xsd:string
http://purl.uniprot.org/citations/25581707http://purl.uniprot.org/core/author"Bechthold A."xsd:string
http://purl.uniprot.org/citations/25581707http://purl.uniprot.org/core/author"Bechthold A."xsd:string
http://purl.uniprot.org/citations/25581707http://purl.uniprot.org/core/author"Gerhardt S."xsd:string
http://purl.uniprot.org/citations/25581707http://purl.uniprot.org/core/author"Gerhardt S."xsd:string
http://purl.uniprot.org/citations/25581707http://purl.uniprot.org/core/author"Thorson J.S."xsd:string
http://purl.uniprot.org/citations/25581707http://purl.uniprot.org/core/author"Thorson J.S."xsd:string
http://purl.uniprot.org/citations/25581707http://purl.uniprot.org/core/author"Rohr J."xsd:string
http://purl.uniprot.org/citations/25581707http://purl.uniprot.org/core/author"Rohr J."xsd:string
http://purl.uniprot.org/citations/25581707http://purl.uniprot.org/core/author"Harle J."xsd:string
http://purl.uniprot.org/citations/25581707http://purl.uniprot.org/core/author"Harle J."xsd:string
http://purl.uniprot.org/citations/25581707http://purl.uniprot.org/core/author"Tam H.K."xsd:string
http://purl.uniprot.org/citations/25581707http://purl.uniprot.org/core/author"Tam H.K."xsd:string
http://purl.uniprot.org/citations/25581707http://purl.uniprot.org/core/author"Bigot A."xsd:string
http://purl.uniprot.org/citations/25581707http://purl.uniprot.org/core/author"Bigot A."xsd:string
http://purl.uniprot.org/citations/25581707http://purl.uniprot.org/core/author"Breit B."xsd:string
http://purl.uniprot.org/citations/25581707http://purl.uniprot.org/core/author"Breit B."xsd:string