| http://purl.uniprot.org/citations/25634694 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/25634694 | http://www.w3.org/2000/01/rdf-schema#comment | "Trophoblast cells are important in embryo implantation and fetomaternal tolerance. HLA-G is specifically expressed at the maternal-fetal interface and is a regulator in pregnancy. The aim of the present study was to detect the effect of HLA-G1 on trophoblast cell proliferation, adhesion, and invasion. Human trophoblast cell lines (JAR and HTR-8/SVneo cells) were infected with HLA-G1-expressing lentivirus. After infection, HLA-G1 expression of the cells was detected by western blotting. Cell proliferation was detected by the BrdU assay. The cell cycle and apoptosis of JAR and HTR-8/SVneo cells was measured by flow cytometry (FCM). The invasion of the cells under different conditions was detected by the transwell invasion chamber assay. HLA-G1 didn't show any significant influence on the proliferation, apoptosis, adhesion, and invasion of trophocytes in normal culture conditions. However, HLA-G1 inhibited JAR and HTR-8/SVneo cells invasion induced by hepatocyte growth factor (HGF) under normal oxygen conditions. In conditions of hypoxia, HLA-G1 couldn't inhibit the induction of cell invasion by HGF. HLA-G1 is not an independent factor for regulating the trophocytes. It may play an indirect role in embryo implantation and formation of the placenta."xsd:string |
| http://purl.uniprot.org/citations/25634694 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.bbrc.2015.01.085"xsd:string |
| http://purl.uniprot.org/citations/25634694 | http://purl.uniprot.org/core/author | "Guo X."xsd:string |
| http://purl.uniprot.org/citations/25634694 | http://purl.uniprot.org/core/author | "Hu Y."xsd:string |
| http://purl.uniprot.org/citations/25634694 | http://purl.uniprot.org/core/author | "Li Y."xsd:string |
| http://purl.uniprot.org/citations/25634694 | http://purl.uniprot.org/core/author | "Jiang F."xsd:string |
| http://purl.uniprot.org/citations/25634694 | http://purl.uniprot.org/core/author | "Yin G."xsd:string |
| http://purl.uniprot.org/citations/25634694 | http://purl.uniprot.org/core/author | "Zhao H."xsd:string |
| http://purl.uniprot.org/citations/25634694 | http://purl.uniprot.org/core/author | "Wang L."xsd:string |
| http://purl.uniprot.org/citations/25634694 | http://purl.uniprot.org/core/author | "Wang X."xsd:string |
| http://purl.uniprot.org/citations/25634694 | http://purl.uniprot.org/core/author | "Yao Y."xsd:string |
| http://purl.uniprot.org/citations/25634694 | http://purl.uniprot.org/core/date | "2015"xsd:gYear |
| http://purl.uniprot.org/citations/25634694 | http://purl.uniprot.org/core/name | "Biochem Biophys Res Commun"xsd:string |
| http://purl.uniprot.org/citations/25634694 | http://purl.uniprot.org/core/pages | "154-160"xsd:string |
| http://purl.uniprot.org/citations/25634694 | http://purl.uniprot.org/core/title | "Role of HLA-G1 in trophoblast cell proliferation, adhesion and invasion."xsd:string |
| http://purl.uniprot.org/citations/25634694 | http://purl.uniprot.org/core/volume | "458"xsd:string |
| http://purl.uniprot.org/citations/25634694 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/25634694 |
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| http://purl.uniprot.org/uniprot/#_A0A0H4M9X9-mappedCitation-25634694 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/25634694 |
| http://purl.uniprot.org/uniprot/#_A0A0H4M9Y0-mappedCitation-25634694 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/25634694 |
| http://purl.uniprot.org/uniprot/#_A0A0H4M9Y1-mappedCitation-25634694 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/25634694 |
| http://purl.uniprot.org/uniprot/#_A0A0H4M9Y2-mappedCitation-25634694 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/25634694 |
| http://purl.uniprot.org/uniprot/#_A0A0H4M9Y3-mappedCitation-25634694 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/25634694 |
| http://purl.uniprot.org/uniprot/#_A0A0H4M9Y6-mappedCitation-25634694 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/25634694 |