| http://purl.uniprot.org/citations/2568126 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/2568126 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/2568126 | http://www.w3.org/2000/01/rdf-schema#comment | "An aqueous exudate collected from frozen and thawed bodies of a Caribbean sea anemone, Stichodactyla (formerly Stoichactis) helianthus, contained a polypeptide neurotoxin (Sh I) selectively toxic to crustaceans. The polypeptide was purified by G-50 Sephadex, phosphocellulose, and sulfopropyl-Sephadex chromatography and shown to have a molecular size of 5200 daltons and a pI of 8.3. The amino acid sequence determined by automatic Edman degradations of whole RCM Sh I and of its clostripain, staphylococcal protease, and cyanogen bromide digest peptides is A1ACKC5DDEGP10DIRTA15PLTGT20VDLGS25CNAGW30EKCAS35YYTII40ADCCR45KKK . Only 33% of this sequence is identical with the sequence of Anemonia sulcata toxin II, a sea anemone toxin isolated from the taxonomic family Actiniidae. The six half-cystines are located in equivalent positions to those of the actiniid toxins and account for nearly half of the residues common to all of the toxins. However, 69% of the Sh I sequence is identical with that of toxin II from Heteractis paumotensis, another sea anemone belonging to the family Stichodactylidae. Stichodactylid toxins lack the initial N-terminal residue of actiniid toxins and possess three consecutive acidic residues at positions 6-8, a single tryptophan at position 30, and four consecutive basic residues at positions 45-48 (C-terminus). A rabbit IgG prepared by Sh I immunization bound Sh I with a K0.5 of 4.7 nM but failed to bind homologous actiniid (Anemonia sulcata II, Condylactis gigantea III) or bolocerid (Bolocera tuedae II) polypeptide neurotoxins.(ABSTRACT TRUNCATED AT 250 WORDS)"xsd:string |
| http://purl.uniprot.org/citations/2568126 | http://purl.org/dc/terms/identifier | "doi:10.1021/bi00434a050"xsd:string |
| http://purl.uniprot.org/citations/2568126 | http://purl.org/dc/terms/identifier | "doi:10.1021/bi00434a050"xsd:string |
| http://purl.uniprot.org/citations/2568126 | http://purl.uniprot.org/core/author | "Dunn B.M."xsd:string |
| http://purl.uniprot.org/citations/2568126 | http://purl.uniprot.org/core/author | "Dunn B.M."xsd:string |
| http://purl.uniprot.org/citations/2568126 | http://purl.uniprot.org/core/author | "Kem W.R."xsd:string |
| http://purl.uniprot.org/citations/2568126 | http://purl.uniprot.org/core/author | "Kem W.R."xsd:string |
| http://purl.uniprot.org/citations/2568126 | http://purl.uniprot.org/core/author | "Price D.A."xsd:string |
| http://purl.uniprot.org/citations/2568126 | http://purl.uniprot.org/core/author | "Price D.A."xsd:string |
| http://purl.uniprot.org/citations/2568126 | http://purl.uniprot.org/core/author | "Pennington M.W."xsd:string |
| http://purl.uniprot.org/citations/2568126 | http://purl.uniprot.org/core/author | "Pennington M.W."xsd:string |
| http://purl.uniprot.org/citations/2568126 | http://purl.uniprot.org/core/author | "Parten B."xsd:string |
| http://purl.uniprot.org/citations/2568126 | http://purl.uniprot.org/core/author | "Parten B."xsd:string |
| http://purl.uniprot.org/citations/2568126 | http://purl.uniprot.org/core/date | "1989"xsd:gYear |
| http://purl.uniprot.org/citations/2568126 | http://purl.uniprot.org/core/date | "1989"xsd:gYear |
| http://purl.uniprot.org/citations/2568126 | http://purl.uniprot.org/core/name | "Biochemistry"xsd:string |
| http://purl.uniprot.org/citations/2568126 | http://purl.uniprot.org/core/name | "Biochemistry"xsd:string |
| http://purl.uniprot.org/citations/2568126 | http://purl.uniprot.org/core/pages | "3483-3489"xsd:string |
| http://purl.uniprot.org/citations/2568126 | http://purl.uniprot.org/core/pages | "3483-3489"xsd:string |
| http://purl.uniprot.org/citations/2568126 | http://purl.uniprot.org/core/title | "Isolation, characterization, and amino acid sequence of a polypeptide neurotoxin occurring in the sea anemone Stichodactyla helianthus."xsd:string |
| http://purl.uniprot.org/citations/2568126 | http://purl.uniprot.org/core/title | "Isolation, characterization, and amino acid sequence of a polypeptide neurotoxin occurring in the sea anemone Stichodactyla helianthus."xsd:string |
| http://purl.uniprot.org/citations/2568126 | http://purl.uniprot.org/core/volume | "28"xsd:string |
| http://purl.uniprot.org/citations/2568126 | http://purl.uniprot.org/core/volume | "28"xsd:string |