Results

RDF/XMLNTriplesTurtleShow queryShare
SubjectPredicateObject
http://purl.uniprot.org/citations/25689900http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/25689900http://www.w3.org/2000/01/rdf-schema#comment"

Aim

Cardiotrophin-1 null mice presented decreased arterial stiffness. The aim of this study is to investigate the relationship between cardiotrophin-1 and arterial stiffness, assessed by brachial-ankle pulse-wave velocity (baPWV).

Methods

We enrolled 300 subjects, 200 with baPWV >1400 and 100 with baPWV ≤1400 cm/s.

Results

Cardiotrophin-1 levels were significantly higher in subjects with baPWV >1400 than those with baPWV ≤1400 cm/s. The multivariate logistic regression analysis showed that age, prehypertension, hypertension and cardiotrophin-1 were independently associated with baPWV >1400 cm/s after adjusting for gender, obesity, diabetes, homeostasis model assessment-insulin resistance, total cholesterol, high-density lipoprotein cholesterol, triglyceride, high-sensitivity C-reactive protein, creatinine, smoking and habitual exercise.

Conclusion

Cardiotrophin-1 is positively related to baPWV independent of traditional cardiometabolic risk factors for arterial stiffness."xsd:string
http://purl.uniprot.org/citations/25689900http://purl.org/dc/terms/identifier"doi:10.2217/bmm.14.87"xsd:string
http://purl.uniprot.org/citations/25689900http://purl.uniprot.org/core/author"Chang C.J."xsd:string
http://purl.uniprot.org/citations/25689900http://purl.uniprot.org/core/author"Yang Y.C."xsd:string
http://purl.uniprot.org/citations/25689900http://purl.uniprot.org/core/author"Lu F.H."xsd:string
http://purl.uniprot.org/citations/25689900http://purl.uniprot.org/core/author"Wu H.T."xsd:string
http://purl.uniprot.org/citations/25689900http://purl.uniprot.org/core/author"Ou H.Y."xsd:string
http://purl.uniprot.org/citations/25689900http://purl.uniprot.org/core/author"Wu J.S."xsd:string
http://purl.uniprot.org/citations/25689900http://purl.uniprot.org/core/author"Hung H.C."xsd:string
http://purl.uniprot.org/citations/25689900http://purl.uniprot.org/core/date"2015"xsd:gYear
http://purl.uniprot.org/citations/25689900http://purl.uniprot.org/core/name"Biomark Med"xsd:string
http://purl.uniprot.org/citations/25689900http://purl.uniprot.org/core/pages"123-130"xsd:string
http://purl.uniprot.org/citations/25689900http://purl.uniprot.org/core/title"Cardiotrophin-1 is associated with increased risk of arterial stiffness."xsd:string
http://purl.uniprot.org/citations/25689900http://purl.uniprot.org/core/volume"9"xsd:string
http://purl.uniprot.org/citations/25689900http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/25689900
http://purl.uniprot.org/citations/25689900http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/25689900
http://purl.uniprot.org/uniprot/#_Q16619-mappedCitation-25689900http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/25689900
http://purl.uniprot.org/uniprot/Q16619http://purl.uniprot.org/core/mappedCitationhttp://purl.uniprot.org/citations/25689900