| http://purl.uniprot.org/citations/2571575 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/2571575 | http://www.w3.org/2000/01/rdf-schema#comment | "To map precisely the mutation locus of eye lens obsolescence (Elo) on mouse chromosome 1, subsequent linkage analysis was achieved using backcross mating between 129/SvSl-Elo (Elo/+) and 129/SvSl (+/+). Mouse genomic DNAs from 17 strains including the Elo mutant mouse were first digested with several restriction enzymes and analyzed by hybridization using gamma 2- and gamma 4-crystallin cDNAs as probes. Restriction endonuclease DraI showed distinct RFLP patterns in both cases. When gamma 2-crystallin cDNA was used as the probe, two strong bands were observed at 4.0 and 2.4 kb in the majority of strains, but the former fragment shifted to the 3.4-kb position in 129/SvSl-Elo (Elo/Elo) and CFO. The polymorphism between 4.0- and 3.4-kb fragments corresponded to the gamma 1-crystallin locus (Cryg-1), and that of the 2.4-kb one, to the gamma 2-crystallin locus (Cryg-2). Mouse DNAs were also analyzed by hybridization using gamma 4-crystallin cDNA (Cryg-4). In this case, 3.4- and 3.0-kb fragments were observed in Elo and wild-type mice, respectively. The backcross offsprings were analyzed with respect to Elo, Idh-1, Cryg-1, and Cryg-4 loci. Among 223 mice analyzed, recombination between Elo and Idh-1 loci was observed in three offsprings; and that between Cryg-1 or Cryg-4 and Idh-1 loci, in one offspring. No recombination occurred between Cryg-1 and Cryg-4 alleles."xsd:string |
| http://purl.uniprot.org/citations/2571575 | http://purl.org/dc/terms/identifier | "doi:10.1016/0888-7543(89)90055-4"xsd:string |
| http://purl.uniprot.org/citations/2571575 | http://purl.uniprot.org/core/author | "Watanabe T."xsd:string |
| http://purl.uniprot.org/citations/2571575 | http://purl.uniprot.org/core/author | "Masaki S."xsd:string |
| http://purl.uniprot.org/citations/2571575 | http://purl.uniprot.org/core/date | "1989"xsd:gYear |
| http://purl.uniprot.org/citations/2571575 | http://purl.uniprot.org/core/name | "Genomics"xsd:string |
| http://purl.uniprot.org/citations/2571575 | http://purl.uniprot.org/core/pages | "259-263"xsd:string |
| http://purl.uniprot.org/citations/2571575 | http://purl.uniprot.org/core/title | "Linkage analysis of the mutation locus in the eye lens obsolescence (Elo) mouse."xsd:string |
| http://purl.uniprot.org/citations/2571575 | http://purl.uniprot.org/core/volume | "5"xsd:string |
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