| http://purl.uniprot.org/citations/25739458 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/25739458 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/25739458 | http://www.w3.org/2000/01/rdf-schema#comment | "Drosophila immune cells, the hemocytes, undergo four stereotypical developmental migrations to populate the embryo, where they provide immune reconnoitering, as well as a number of non-immune-related functions necessary for proper embryogenesis. Here, we describe a role for Rho1 in one of these developmental migrations in which posteriorly located hemocytes migrate toward the head. This migration requires the interaction of Rho1 with its downstream effector Wash, a Wiskott-Aldrich syndrome family protein. Both Wash knockdown and a Rho1 transgene harboring a mutation that prevents Wash binding exhibit the same developmental migratory defect as Rho1 knockdown. Wash activates the Arp2/3 complex, whose activity is needed for this migration, whereas members of the WASH regulatory complex (SWIP, Strumpellin, and CCDC53) are not. Our results suggest a WASH complex-independent signaling pathway to regulate the cytoskeleton during a subset of hemocyte developmental migrations."xsd:string |
| http://purl.uniprot.org/citations/25739458 | http://purl.org/dc/terms/identifier | "doi:10.1091/mbc.e14-08-1266"xsd:string |
| http://purl.uniprot.org/citations/25739458 | http://purl.org/dc/terms/identifier | "doi:10.1091/mbc.e14-08-1266"xsd:string |
| http://purl.uniprot.org/citations/25739458 | http://purl.uniprot.org/core/author | "Parkhurst S.M."xsd:string |
| http://purl.uniprot.org/citations/25739458 | http://purl.uniprot.org/core/author | "Parkhurst S.M."xsd:string |
| http://purl.uniprot.org/citations/25739458 | http://purl.uniprot.org/core/author | "Rahe T.K."xsd:string |
| http://purl.uniprot.org/citations/25739458 | http://purl.uniprot.org/core/author | "Rahe T.K."xsd:string |
| http://purl.uniprot.org/citations/25739458 | http://purl.uniprot.org/core/author | "Rodriguez-Mesa E."xsd:string |
| http://purl.uniprot.org/citations/25739458 | http://purl.uniprot.org/core/author | "Rodriguez-Mesa E."xsd:string |
| http://purl.uniprot.org/citations/25739458 | http://purl.uniprot.org/core/author | "Verboon J.M."xsd:string |
| http://purl.uniprot.org/citations/25739458 | http://purl.uniprot.org/core/author | "Verboon J.M."xsd:string |
| http://purl.uniprot.org/citations/25739458 | http://purl.uniprot.org/core/date | "2015"xsd:gYear |
| http://purl.uniprot.org/citations/25739458 | http://purl.uniprot.org/core/date | "2015"xsd:gYear |
| http://purl.uniprot.org/citations/25739458 | http://purl.uniprot.org/core/name | "Mol. Biol. Cell"xsd:string |
| http://purl.uniprot.org/citations/25739458 | http://purl.uniprot.org/core/name | "Mol. Biol. Cell"xsd:string |
| http://purl.uniprot.org/citations/25739458 | http://purl.uniprot.org/core/pages | "1665-1674"xsd:string |
| http://purl.uniprot.org/citations/25739458 | http://purl.uniprot.org/core/pages | "1665-1674"xsd:string |
| http://purl.uniprot.org/citations/25739458 | http://purl.uniprot.org/core/title | "Wash functions downstream of Rho1 GTPase in a subset of Drosophila immune cell developmental migrations."xsd:string |
| http://purl.uniprot.org/citations/25739458 | http://purl.uniprot.org/core/title | "Wash functions downstream of Rho1 GTPase in a subset of Drosophila immune cell developmental migrations."xsd:string |
| http://purl.uniprot.org/citations/25739458 | http://purl.uniprot.org/core/volume | "26"xsd:string |
| http://purl.uniprot.org/citations/25739458 | http://purl.uniprot.org/core/volume | "26"xsd:string |
| http://purl.uniprot.org/citations/25739458 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/25739458 |
| http://purl.uniprot.org/citations/25739458 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/25739458 |