| http://purl.uniprot.org/citations/2575515 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/2575515 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/2575515 | http://www.w3.org/2000/01/rdf-schema#comment | "We have isolated, sequenced and examined the expression pattern of two tandemly arranged homeobox-containing genes from the chicken. The predicted amino acid sequences of the homeodomain and the adjacent carboxyterminal portion of the protein of the first gene is virtually identical (99%) to that of murine homeobox 2.1 and hence we refer to it as Ghox 2.1 (Gallus homeobox). The closest mouse homologue of the second homeodomain is Hox 2.2 (95% identical within the homeobox), and hence referred to as Ghox 2.2. Northern analysis of embryonic RNA reveals major transcripts of 2 kb for Ghox 2.1 and 1.7 kb for Ghox 2.2. To investigate the transcript pattern, embryos of various stages were dissected into heads, trunks and limb buds and the RNA was analysed by Northern blotting and RNase protection assays. Ghox 2.1 transcripts are present in all three regions. Ghox 2.2 RNA is found in trunks and limb buds, but it is strikingly absent from the developing head. In situ hybridization with 35S-labelled antisense riboprobes derived from Ghox 2.1 demonstrates that this gene is expressed at high levels in spinal chord, myelencephalon and mesonephros. Dorsal root ganglia and the lung rudiment also contain Ghox 2.1 message, but in somewhat lower amounts. Mid- and forebrain, the heart, presomitic mesenchyme and notochord do not contain detectable levels of Ghox 2.1 mRNA. Of particular interest is the expression of Ghox 2.1 in a well-defined patch of mesenchymal tissue situated in an anterioproximal region of the limb bud."xsd:string |
| http://purl.uniprot.org/citations/2575515 | http://purl.org/dc/terms/identifier | "doi:10.1242/dev.105.3.639"xsd:string |
| http://purl.uniprot.org/citations/2575515 | http://purl.org/dc/terms/identifier | "doi:10.1242/dev.105.3.639"xsd:string |
| http://purl.uniprot.org/citations/2575515 | http://purl.uniprot.org/core/author | "Eichele G."xsd:string |
| http://purl.uniprot.org/citations/2575515 | http://purl.uniprot.org/core/author | "Eichele G."xsd:string |
| http://purl.uniprot.org/citations/2575515 | http://purl.uniprot.org/core/author | "Pang K."xsd:string |
| http://purl.uniprot.org/citations/2575515 | http://purl.uniprot.org/core/author | "Pang K."xsd:string |
| http://purl.uniprot.org/citations/2575515 | http://purl.uniprot.org/core/author | "Wedden S.E."xsd:string |
| http://purl.uniprot.org/citations/2575515 | http://purl.uniprot.org/core/author | "Wedden S.E."xsd:string |
| http://purl.uniprot.org/citations/2575515 | http://purl.uniprot.org/core/date | "1989"xsd:gYear |
| http://purl.uniprot.org/citations/2575515 | http://purl.uniprot.org/core/date | "1989"xsd:gYear |
| http://purl.uniprot.org/citations/2575515 | http://purl.uniprot.org/core/name | "Development"xsd:string |
| http://purl.uniprot.org/citations/2575515 | http://purl.uniprot.org/core/name | "Development"xsd:string |
| http://purl.uniprot.org/citations/2575515 | http://purl.uniprot.org/core/pages | "639-650"xsd:string |
| http://purl.uniprot.org/citations/2575515 | http://purl.uniprot.org/core/pages | "639-650"xsd:string |
| http://purl.uniprot.org/citations/2575515 | http://purl.uniprot.org/core/title | "Expression pattern of homeobox-containing genes during chick embryogenesis."xsd:string |
| http://purl.uniprot.org/citations/2575515 | http://purl.uniprot.org/core/title | "Expression pattern of homeobox-containing genes during chick embryogenesis."xsd:string |
| http://purl.uniprot.org/citations/2575515 | http://purl.uniprot.org/core/volume | "105"xsd:string |
| http://purl.uniprot.org/citations/2575515 | http://purl.uniprot.org/core/volume | "105"xsd:string |
| http://purl.uniprot.org/citations/2575515 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/2575515 |
| http://purl.uniprot.org/citations/2575515 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/2575515 |
| http://purl.uniprot.org/citations/2575515 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/2575515 |
| http://purl.uniprot.org/citations/2575515 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/2575515 |