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http://purl.uniprot.org/citations/25776493http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/25776493http://www.w3.org/2000/01/rdf-schema#comment"Our previous studies have shown that decreased expression of Annexin A7 elevates apoptosis in Hca-P cells, a hepatocarcinoma cell line with lymphatic metastatic potential. In this study, RNA interference technique was used to down-regulate the expression of Annexin A7, and unmanipulated Hca-P cells and transfected nonspecific-sequence Hca-P cells as control. The down-regulation of Annexin A7 declined the cell viability after cisplatin exposure. And the reduced expression of Annexin A7 decreased the expression of Bcl2, increased the expression of Cytochrome-C in the cytoplasme, and then improved the expression of Caspase-3. However there was no significant effect on the expression of Bax, Caspase-12, Fas, FasL and Caspase-8. The results indicate that the decreased expression of Annexin A7 could inhibit the proliferation, and increase the apoptosis of Hca-P cells by affecting the expression of the apoptosis associated proteins by the mitochondrial pathway."xsd:string
http://purl.uniprot.org/citations/25776493http://purl.org/dc/terms/identifier"doi:10.1016/j.biopha.2015.01.009"xsd:string
http://purl.uniprot.org/citations/25776493http://purl.uniprot.org/core/author"Du Y."xsd:string
http://purl.uniprot.org/citations/25776493http://purl.uniprot.org/core/author"Huang Y."xsd:string
http://purl.uniprot.org/citations/25776493http://purl.uniprot.org/core/author"Li C."xsd:string
http://purl.uniprot.org/citations/25776493http://purl.uniprot.org/core/author"Wei Y."xsd:string
http://purl.uniprot.org/citations/25776493http://purl.uniprot.org/core/author"Zhang X."xsd:string
http://purl.uniprot.org/citations/25776493http://purl.uniprot.org/core/author"Zhang J."xsd:string
http://purl.uniprot.org/citations/25776493http://purl.uniprot.org/core/author"Wang H."xsd:string
http://purl.uniprot.org/citations/25776493http://purl.uniprot.org/core/author"Zhao Z."xsd:string
http://purl.uniprot.org/citations/25776493http://purl.uniprot.org/core/author"Tang J."xsd:string
http://purl.uniprot.org/citations/25776493http://purl.uniprot.org/core/author"Fan S."xsd:string
http://purl.uniprot.org/citations/25776493http://purl.uniprot.org/core/author"Bai L."xsd:string
http://purl.uniprot.org/citations/25776493http://purl.uniprot.org/core/author"Mibrahim M."xsd:string
http://purl.uniprot.org/citations/25776493http://purl.uniprot.org/core/date"2015"xsd:gYear
http://purl.uniprot.org/citations/25776493http://purl.uniprot.org/core/name"Biomed Pharmacother"xsd:string
http://purl.uniprot.org/citations/25776493http://purl.uniprot.org/core/pages"146-150"xsd:string
http://purl.uniprot.org/citations/25776493http://purl.uniprot.org/core/title"Down-regulated expression of Annexin A7 induces apoptosis in mouse hepatocarcinoma cell line by the intrinsic mitochondrial pathway."xsd:string
http://purl.uniprot.org/citations/25776493http://purl.uniprot.org/core/volume"70"xsd:string
http://purl.uniprot.org/citations/25776493http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/25776493
http://purl.uniprot.org/citations/25776493http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/25776493
http://purl.uniprot.org/uniprot/#_A0A2C9F2D2-mappedCitation-25776493http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/25776493
http://purl.uniprot.org/uniprot/#_Q8BP75-mappedCitation-25776493http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/25776493
http://purl.uniprot.org/uniprot/#_Q922A2-mappedCitation-25776493http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/25776493