http://purl.uniprot.org/citations/25776493 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/25776493 | http://www.w3.org/2000/01/rdf-schema#comment | "Our previous studies have shown that decreased expression of Annexin A7 elevates apoptosis in Hca-P cells, a hepatocarcinoma cell line with lymphatic metastatic potential. In this study, RNA interference technique was used to down-regulate the expression of Annexin A7, and unmanipulated Hca-P cells and transfected nonspecific-sequence Hca-P cells as control. The down-regulation of Annexin A7 declined the cell viability after cisplatin exposure. And the reduced expression of Annexin A7 decreased the expression of Bcl2, increased the expression of Cytochrome-C in the cytoplasme, and then improved the expression of Caspase-3. However there was no significant effect on the expression of Bax, Caspase-12, Fas, FasL and Caspase-8. The results indicate that the decreased expression of Annexin A7 could inhibit the proliferation, and increase the apoptosis of Hca-P cells by affecting the expression of the apoptosis associated proteins by the mitochondrial pathway."xsd:string |
http://purl.uniprot.org/citations/25776493 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.biopha.2015.01.009"xsd:string |
http://purl.uniprot.org/citations/25776493 | http://purl.uniprot.org/core/author | "Du Y."xsd:string |
http://purl.uniprot.org/citations/25776493 | http://purl.uniprot.org/core/author | "Huang Y."xsd:string |
http://purl.uniprot.org/citations/25776493 | http://purl.uniprot.org/core/author | "Li C."xsd:string |
http://purl.uniprot.org/citations/25776493 | http://purl.uniprot.org/core/author | "Wei Y."xsd:string |
http://purl.uniprot.org/citations/25776493 | http://purl.uniprot.org/core/author | "Zhang X."xsd:string |
http://purl.uniprot.org/citations/25776493 | http://purl.uniprot.org/core/author | "Zhang J."xsd:string |
http://purl.uniprot.org/citations/25776493 | http://purl.uniprot.org/core/author | "Wang H."xsd:string |
http://purl.uniprot.org/citations/25776493 | http://purl.uniprot.org/core/author | "Zhao Z."xsd:string |
http://purl.uniprot.org/citations/25776493 | http://purl.uniprot.org/core/author | "Tang J."xsd:string |
http://purl.uniprot.org/citations/25776493 | http://purl.uniprot.org/core/author | "Fan S."xsd:string |
http://purl.uniprot.org/citations/25776493 | http://purl.uniprot.org/core/author | "Bai L."xsd:string |
http://purl.uniprot.org/citations/25776493 | http://purl.uniprot.org/core/author | "Mibrahim M."xsd:string |
http://purl.uniprot.org/citations/25776493 | http://purl.uniprot.org/core/date | "2015"xsd:gYear |
http://purl.uniprot.org/citations/25776493 | http://purl.uniprot.org/core/name | "Biomed Pharmacother"xsd:string |
http://purl.uniprot.org/citations/25776493 | http://purl.uniprot.org/core/pages | "146-150"xsd:string |
http://purl.uniprot.org/citations/25776493 | http://purl.uniprot.org/core/title | "Down-regulated expression of Annexin A7 induces apoptosis in mouse hepatocarcinoma cell line by the intrinsic mitochondrial pathway."xsd:string |
http://purl.uniprot.org/citations/25776493 | http://purl.uniprot.org/core/volume | "70"xsd:string |
http://purl.uniprot.org/citations/25776493 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/25776493 |
http://purl.uniprot.org/citations/25776493 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/25776493 |
http://purl.uniprot.org/uniprot/#_A0A2C9F2D2-mappedCitation-25776493 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/25776493 |
http://purl.uniprot.org/uniprot/#_Q8BP75-mappedCitation-25776493 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/25776493 |
http://purl.uniprot.org/uniprot/#_Q922A2-mappedCitation-25776493 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/25776493 |