| http://purl.uniprot.org/citations/25874486 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/25874486 | http://www.w3.org/2000/01/rdf-schema#comment | "The aim of this study is to investigate the effects of inhibiting Aurora-B on osteosarcoma (OS) cell malignant phenotype, phosphorylation of valosin-containing protein (VCP), and the activity of NF-κB signaling in vitro. The expressions of Aurora-B and p-VCP proteins were detected by immunohistochemistry in 24 OS tissues, and the relationship between Aurora-B and p-VCP was investigated. The results showed that there was a positive correlation between Aurora-B and p-VCP proteins. The expression of Aurora-B in human OS cell lines U2-OS and HOS cells was inhibited by specific short hairpin RNA (shRNA) lentivirus (AURKB-shRNA lentivirus, Lv-shAURKB) which targeted Aurora-B. The results showed that the phosphorylation of VCP, the activity of NF-κB signaling pathway and the malignant phenotype of OS cells were all suppressed by knockdown of Aurora-B. It indicated that the inhibition of Aurora-B alters OS cells malignant phenotype by downregulating phosphorylation of VCP and activating of the NF-κB signaling pathway in vitro."xsd:string |
| http://purl.uniprot.org/citations/25874486 | http://purl.org/dc/terms/identifier | "doi:10.1007/s13277-014-3032-4"xsd:string |
| http://purl.uniprot.org/citations/25874486 | http://purl.uniprot.org/core/author | "Zhu X.P."xsd:string |
| http://purl.uniprot.org/citations/25874486 | http://purl.uniprot.org/core/author | "He J.Y."xsd:string |
| http://purl.uniprot.org/citations/25874486 | http://purl.uniprot.org/core/author | "Liu Z.L."xsd:string |
| http://purl.uniprot.org/citations/25874486 | http://purl.uniprot.org/core/author | "Chen X.Y."xsd:string |
| http://purl.uniprot.org/citations/25874486 | http://purl.uniprot.org/core/author | "Liu J.M."xsd:string |
| http://purl.uniprot.org/citations/25874486 | http://purl.uniprot.org/core/author | "Xi W.H."xsd:string |
| http://purl.uniprot.org/citations/25874486 | http://purl.uniprot.org/core/author | "Luo Q.F."xsd:string |
| http://purl.uniprot.org/citations/25874486 | http://purl.uniprot.org/core/author | "Long X.H."xsd:string |
| http://purl.uniprot.org/citations/25874486 | http://purl.uniprot.org/core/author | "Zhu L.B."xsd:string |
| http://purl.uniprot.org/citations/25874486 | http://purl.uniprot.org/core/date | "2015"xsd:gYear |
| http://purl.uniprot.org/citations/25874486 | http://purl.uniprot.org/core/name | "Tumour Biol"xsd:string |
| http://purl.uniprot.org/citations/25874486 | http://purl.uniprot.org/core/pages | "3895-3902"xsd:string |
| http://purl.uniprot.org/citations/25874486 | http://purl.uniprot.org/core/title | "Knockdown of Aurora-B alters osteosarcoma cell malignant phenotype via decreasing phosphorylation of VCP and NF-kappaB signaling."xsd:string |
| http://purl.uniprot.org/citations/25874486 | http://purl.uniprot.org/core/volume | "36"xsd:string |
| http://purl.uniprot.org/citations/25874486 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/25874486 |
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| http://purl.uniprot.org/uniprot/#_Q96IF9-mappedCitation-25874486 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/25874486 |
| http://purl.uniprot.org/uniprot/#_Q9HAP0-mappedCitation-25874486 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/25874486 |
| http://purl.uniprot.org/uniprot/#_Q9HAP1-mappedCitation-25874486 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/25874486 |