http://purl.uniprot.org/citations/25880496 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/25880496 | http://www.w3.org/2000/01/rdf-schema#comment | "The human α/β hydrolase domain-containing protein 2 gene (ABHD2) plays a critical role in pulmonary emphysema, a major subset of the clinical entity known as chronic obstructive pulmonary disease (COPD). Here, we evaluated genetic variation in the ABHD2 gene in a Chinese Han population of 286 COPD patients and 326 control subjects. The rs12442260 CT/CC genotype was associated with COPD (P < 0.001) under a dominant model. In the former-smoker group, the rs12442260 TT genotype was associated with a decreased risk of developing COPD after adjusting for age, gender and pack-years (P = 0.012). Rs12442260 was also associated with pre-FEV1 (the predicted bronchodilator forced expiratory volume in the first second) in controls (P = 0.027), but with FEV1/ forced vital capacity (FVC) ratios only in COPD patients (P = 0.012) under a dominant model. Results from the current study suggest that ABHD2 gene polymorphisms contribute to COPD susceptibility in the Chinese Han population."xsd:string |
http://purl.uniprot.org/citations/25880496 | http://purl.org/dc/terms/identifier | "doi:10.1371/journal.pone.0123929"xsd:string |
http://purl.uniprot.org/citations/25880496 | http://purl.uniprot.org/core/author | "Jin S."xsd:string |
http://purl.uniprot.org/citations/25880496 | http://purl.uniprot.org/core/author | "Li X."xsd:string |
http://purl.uniprot.org/citations/25880496 | http://purl.uniprot.org/core/author | "Liu L."xsd:string |
http://purl.uniprot.org/citations/25880496 | http://purl.uniprot.org/core/author | "Shen J."xsd:string |
http://purl.uniprot.org/citations/25880496 | http://purl.uniprot.org/core/author | "Zhang H."xsd:string |
http://purl.uniprot.org/citations/25880496 | http://purl.uniprot.org/core/author | "Yuan R."xsd:string |
http://purl.uniprot.org/citations/25880496 | http://purl.uniprot.org/core/author | "Qiang L."xsd:string |
http://purl.uniprot.org/citations/25880496 | http://purl.uniprot.org/core/date | "2015"xsd:gYear |
http://purl.uniprot.org/citations/25880496 | http://purl.uniprot.org/core/name | "PLoS One"xsd:string |
http://purl.uniprot.org/citations/25880496 | http://purl.uniprot.org/core/pages | "e0123929"xsd:string |
http://purl.uniprot.org/citations/25880496 | http://purl.uniprot.org/core/title | "Associations of ABHD2 genetic variations with risks for chronic obstructive pulmonary disease in a Chinese Han population."xsd:string |
http://purl.uniprot.org/citations/25880496 | http://purl.uniprot.org/core/volume | "10"xsd:string |
http://purl.uniprot.org/citations/25880496 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/25880496 |
http://purl.uniprot.org/citations/25880496 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/25880496 |
http://purl.uniprot.org/uniprot/#_A0A024RC89-mappedCitation-25880496 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/25880496 |
http://purl.uniprot.org/uniprot/#_A8K2S5-mappedCitation-25880496 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/25880496 |
http://purl.uniprot.org/uniprot/#_B4DL35-mappedCitation-25880496 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/25880496 |
http://purl.uniprot.org/uniprot/#_P08910-mappedCitation-25880496 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/25880496 |
http://purl.uniprot.org/uniprot/B4DL35 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/25880496 |
http://purl.uniprot.org/uniprot/A0A024RC89 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/25880496 |
http://purl.uniprot.org/uniprot/P08910 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/25880496 |
http://purl.uniprot.org/uniprot/A8K2S5 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/25880496 |