| http://purl.uniprot.org/citations/25888259 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/25888259 | http://www.w3.org/2000/01/rdf-schema#comment | "The interleukin-17 (IL-17) family of cytokines has emerged as a critical player in inflammatory diseases. Among them, IL-25 has been shown to be important in allergic inflammation and protection against parasitic infection. Here we have demonstrated that IL-17B, a poorly understood cytokine, functions to inhibit IL-25-driven inflammation. IL-17B and IL-25, both binding to the interleukin-17 receptor B (IL-17RB), were upregulated in their expression after acute colonic inflammation. Individual inhibition of these cytokines revealed opposing functions in colon inflammation: IL-25 was pathogenic but IL-17B was protective. Similarly opposing phenotypes were observed in Citrobacter rodentium infection and allergic asthma. Moreover, IL-25 was found to promote IL-6 production from colon epithelial cells, which was inhibited by IL-17B. Therefore, our data demonstrate that IL-17B is an anti-inflammatory cytokine in the IL-17 family."xsd:string |
| http://purl.uniprot.org/citations/25888259 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.immuni.2015.03.008"xsd:string |
| http://purl.uniprot.org/citations/25888259 | http://purl.uniprot.org/core/author | "Shi Y."xsd:string |
| http://purl.uniprot.org/citations/25888259 | http://purl.uniprot.org/core/author | "Wang X."xsd:string |
| http://purl.uniprot.org/citations/25888259 | http://purl.uniprot.org/core/author | "Chang S.H."xsd:string |
| http://purl.uniprot.org/citations/25888259 | http://purl.uniprot.org/core/author | "Lee Y.H."xsd:string |
| http://purl.uniprot.org/citations/25888259 | http://purl.uniprot.org/core/author | "Dong C."xsd:string |
| http://purl.uniprot.org/citations/25888259 | http://purl.uniprot.org/core/author | "Reynolds J.M."xsd:string |
| http://purl.uniprot.org/citations/25888259 | http://purl.uniprot.org/core/author | "Watarai H."xsd:string |
| http://purl.uniprot.org/citations/25888259 | http://purl.uniprot.org/core/author | "Angkasekwinai P."xsd:string |
| http://purl.uniprot.org/citations/25888259 | http://purl.uniprot.org/core/author | "Flaherty S."xsd:string |
| http://purl.uniprot.org/citations/25888259 | http://purl.uniprot.org/core/author | "Nallaparaju K.C."xsd:string |
| http://purl.uniprot.org/citations/25888259 | http://purl.uniprot.org/core/date | "2015"xsd:gYear |
| http://purl.uniprot.org/citations/25888259 | http://purl.uniprot.org/core/name | "Immunity"xsd:string |
| http://purl.uniprot.org/citations/25888259 | http://purl.uniprot.org/core/pages | "692-703"xsd:string |
| http://purl.uniprot.org/citations/25888259 | http://purl.uniprot.org/core/title | "Interleukin-17B Antagonizes Interleukin-25-Mediated Mucosal Inflammation."xsd:string |
| http://purl.uniprot.org/citations/25888259 | http://purl.uniprot.org/core/volume | "42"xsd:string |
| http://purl.uniprot.org/citations/25888259 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/25888259 |
| http://purl.uniprot.org/citations/25888259 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/25888259 |
| http://purl.uniprot.org/uniprot/#_A0A494B960-mappedCitation-25888259 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/25888259 |
| http://purl.uniprot.org/uniprot/#_D6RCY5-mappedCitation-25888259 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/25888259 |
| http://purl.uniprot.org/uniprot/#_D6REG3-mappedCitation-25888259 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/25888259 |
| http://purl.uniprot.org/uniprot/#_D3Z4T0-mappedCitation-25888259 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/25888259 |
| http://purl.uniprot.org/uniprot/#_I7GPR1-mappedCitation-25888259 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/25888259 |