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| http://purl.uniprot.org/citations/2591369 | http://www.w3.org/2000/01/rdf-schema#comment | "A murine linkage map generated from analyses of 428 meiotic events in an interspecific cross and pulsed field gel electrophoresis allowed examination of the genomic organization of a 6000 kb segment of mouse and human chromosome 1. Analysis of five genes within this syntenic segment of both species revealed striking conservation of gene order, intergenic distance and, to a lesser extent, CpG dinucleotides. In the mouse, meiotic crossover events were not evenly distributed; a hot spot for meiotic recombination was coincident with a CpG-island. These studies provide a practical approach to aid physical mapping of the human genome and a model for determining the molecular principles that govern meiotic recombination. In addition, these findings demonstrate profound conservation of genomic organization over mammalian evolution."xsd:string |
| http://purl.uniprot.org/citations/2591369 | http://purl.org/dc/terms/identifier | "doi:10.1002/j.1460-2075.1989.tb08591.x"xsd:string |
| http://purl.uniprot.org/citations/2591369 | http://purl.uniprot.org/core/author | "Seldin M.F."xsd:string |
| http://purl.uniprot.org/citations/2591369 | http://purl.uniprot.org/core/author | "Kingsmore S.F."xsd:string |
| http://purl.uniprot.org/citations/2591369 | http://purl.uniprot.org/core/author | "Howard T.A."xsd:string |
| http://purl.uniprot.org/citations/2591369 | http://purl.uniprot.org/core/author | "Watson M.L."xsd:string |
| http://purl.uniprot.org/citations/2591369 | http://purl.uniprot.org/core/date | "1989"xsd:gYear |
| http://purl.uniprot.org/citations/2591369 | http://purl.uniprot.org/core/name | "EMBO J"xsd:string |
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| http://purl.uniprot.org/citations/2591369 | http://purl.uniprot.org/core/title | "A 6000 kb segment of chromosome 1 is conserved in human and mouse."xsd:string |
| http://purl.uniprot.org/citations/2591369 | http://purl.uniprot.org/core/volume | "8"xsd:string |
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