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http://purl.uniprot.org/citations/2597281http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/2597281http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/2597281http://www.w3.org/2000/01/rdf-schema#comment"A tetrapeptide named achatin-I was purified from the suboesophageal and cerebral ganglia of the African giant snail Achatina fulica Férussac, and evoked a potent neuroexcitatory effect. The amino acid sequence of achatin-I is Gly-D-Phe-Ala-Asp. Achatin-I induced a voltage-dependent inward current, due to Na+, on the identifiable giant neuron, periodically oscillating neuron (PON), of the same snail. All possible isomers of achatin-I were synthesized using the solid-phase method. The sensitivity of the neuron to achatin-I and its isomers was strictly stereospecific; among the various isomers, only achatin-I showed marked effects (ED50 = 2.29 x 10(-6)M), while Gly-D-Phe-D-Ala-Asp, the synthetic D-Ala-isomer, was less than 10(-3) active."xsd:string
http://purl.uniprot.org/citations/2597281http://purl.org/dc/terms/identifier"doi:10.1016/s0006-291x(89)80103-2"xsd:string
http://purl.uniprot.org/citations/2597281http://purl.org/dc/terms/identifier"doi:10.1016/s0006-291x(89)80103-2"xsd:string
http://purl.uniprot.org/citations/2597281http://purl.uniprot.org/core/author"Kim K.H."xsd:string
http://purl.uniprot.org/citations/2597281http://purl.uniprot.org/core/author"Kim K.H."xsd:string
http://purl.uniprot.org/citations/2597281http://purl.uniprot.org/core/author"Watanabe K."xsd:string
http://purl.uniprot.org/citations/2597281http://purl.uniprot.org/core/author"Watanabe K."xsd:string
http://purl.uniprot.org/citations/2597281http://purl.uniprot.org/core/author"Takeuchi H."xsd:string
http://purl.uniprot.org/citations/2597281http://purl.uniprot.org/core/author"Takeuchi H."xsd:string
http://purl.uniprot.org/citations/2597281http://purl.uniprot.org/core/author"Funase K."xsd:string
http://purl.uniprot.org/citations/2597281http://purl.uniprot.org/core/author"Funase K."xsd:string
http://purl.uniprot.org/citations/2597281http://purl.uniprot.org/core/author"Iwashita T."xsd:string
http://purl.uniprot.org/citations/2597281http://purl.uniprot.org/core/author"Iwashita T."xsd:string
http://purl.uniprot.org/citations/2597281http://purl.uniprot.org/core/author"Kamatani Y."xsd:string
http://purl.uniprot.org/citations/2597281http://purl.uniprot.org/core/author"Kamatani Y."xsd:string
http://purl.uniprot.org/citations/2597281http://purl.uniprot.org/core/author"Kanapi C.G."xsd:string
http://purl.uniprot.org/citations/2597281http://purl.uniprot.org/core/author"Kanapi C.G."xsd:string
http://purl.uniprot.org/citations/2597281http://purl.uniprot.org/core/author"Kenny P.T.M."xsd:string
http://purl.uniprot.org/citations/2597281http://purl.uniprot.org/core/author"Kenny P.T.M."xsd:string
http://purl.uniprot.org/citations/2597281http://purl.uniprot.org/core/author"Minakata H."xsd:string
http://purl.uniprot.org/citations/2597281http://purl.uniprot.org/core/author"Minakata H."xsd:string
http://purl.uniprot.org/citations/2597281http://purl.uniprot.org/core/author"Nomoto K."xsd:string
http://purl.uniprot.org/citations/2597281http://purl.uniprot.org/core/author"Nomoto K."xsd:string