| http://purl.uniprot.org/citations/25975613 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/25975613 | http://www.w3.org/2000/01/rdf-schema#comment | "Condensin is not only responsible for chromosome condensation, but is also involved in double-strand break (DSB) processing in the cell cycle. During meiosis, the condensin complex serves as a component of the meiotic chromosome axis, and mediates both proper assembly of the synaptonemal complex and DSB repair, in order to ensure proper homologous chromosome segregation. Here, we used the budding yeast Saccharomyces cerevisiae to show that condensin participates in a variety of chromosome organization processes and exhibits crucial molecular functions that contribute to meiotic recombination during meiotic prophase I. We demonstrate that Ycs4 is required for efficient DSB formation and establishing homolog bias at the early stage of meiotic prophase I, which allows efficient formation of interhomolog recombination products. In the Ycs4 meiosis-specific allele (ycs4S), interhomolog products were formed at substantial levels, but with the same reduction in crossovers and noncrossovers. We further show that, in prophase chromosomal events, ycs4S relieved the defects in the progression of recombination interactions induced as a result of the absence of Rec8. These results suggest that condensin is a crucial coordinator of the recombination process and chromosome organization during meiosis."xsd:string |
| http://purl.uniprot.org/citations/25975613 | http://purl.org/dc/terms/identifier | "doi:10.4014/jmb.1504.04013"xsd:string |
| http://purl.uniprot.org/citations/25975613 | http://purl.uniprot.org/core/author | "Hong S."xsd:string |
| http://purl.uniprot.org/citations/25975613 | http://purl.uniprot.org/core/author | "Kim K.P."xsd:string |
| http://purl.uniprot.org/citations/25975613 | http://purl.uniprot.org/core/author | "Choi E.H."xsd:string |
| http://purl.uniprot.org/citations/25975613 | http://purl.uniprot.org/core/date | "2015"xsd:gYear |
| http://purl.uniprot.org/citations/25975613 | http://purl.uniprot.org/core/name | "J Microbiol Biotechnol"xsd:string |
| http://purl.uniprot.org/citations/25975613 | http://purl.uniprot.org/core/pages | "1026-1035"xsd:string |
| http://purl.uniprot.org/citations/25975613 | http://purl.uniprot.org/core/title | "Ycs4 is Required for Efficient Double-Strand Break Formation and Homologous Recombination During Meiosis."xsd:string |
| http://purl.uniprot.org/citations/25975613 | http://purl.uniprot.org/core/volume | "25"xsd:string |
| http://purl.uniprot.org/citations/25975613 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/25975613 |
| http://purl.uniprot.org/citations/25975613 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/25975613 |
| http://purl.uniprot.org/uniprot/#_A0A8H4FBP5-mappedCitation-25975613 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/25975613 |
| http://purl.uniprot.org/uniprot/#_Q12188-mappedCitation-25975613 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/25975613 |
| http://purl.uniprot.org/uniprot/#_Q06156-mappedCitation-25975613 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/25975613 |
| http://purl.uniprot.org/uniprot/A0A8H4FBP5 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/25975613 |
| http://purl.uniprot.org/uniprot/Q06156 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/25975613 |
| http://purl.uniprot.org/uniprot/Q12188 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/25975613 |