| http://purl.uniprot.org/citations/25992613 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/25992613 | http://www.w3.org/2000/01/rdf-schema#comment | "miRNAs play a central role in numerous pathologies including multiple cancer types. miR-191 has predominantly been studied as an oncogene, but the role of miR-191 in the proliferation of primary cells is not well characterized, and the miR-191 targetome has not been experimentally profiled. Here we utilized RNA induced silencing complex immunoprecipitations as well as gene expression profiling to construct a genome wide miR-191 target profile. We show that miR-191 represses proliferation in primary human fibroblasts, identify multiple proto-oncogenes as novel miR-191 targets, including CDK9, NOTCH2, and RPS6KA3, and present evidence that miR-191 extensively mediates target expression through coding sequence (CDS) pairing. Our results provide a comprehensive genome wide miR-191 target profile, and demonstrate miR-191's regulation of primary human fibroblast proliferation."xsd:string |
| http://purl.uniprot.org/citations/25992613 | http://purl.org/dc/terms/identifier | "doi:10.1371/journal.pone.0126535"xsd:string |
| http://purl.uniprot.org/citations/25992613 | http://purl.uniprot.org/core/author | "Iyer V.R."xsd:string |
| http://purl.uniprot.org/citations/25992613 | http://purl.uniprot.org/core/author | "Abell N.S."xsd:string |
| http://purl.uniprot.org/citations/25992613 | http://purl.uniprot.org/core/author | "Polioudakis D."xsd:string |
| http://purl.uniprot.org/citations/25992613 | http://purl.uniprot.org/core/date | "2015"xsd:gYear |
| http://purl.uniprot.org/citations/25992613 | http://purl.uniprot.org/core/name | "PLoS One"xsd:string |
| http://purl.uniprot.org/citations/25992613 | http://purl.uniprot.org/core/pages | "e0126535"xsd:string |
| http://purl.uniprot.org/citations/25992613 | http://purl.uniprot.org/core/title | "MiR-191 Regulates Primary Human Fibroblast Proliferation and Directly Targets Multiple Oncogenes."xsd:string |
| http://purl.uniprot.org/citations/25992613 | http://purl.uniprot.org/core/volume | "10"xsd:string |
| http://purl.uniprot.org/citations/25992613 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/25992613 |
| http://purl.uniprot.org/citations/25992613 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/25992613 |
| http://purl.uniprot.org/uniprot/#_B2R9L6-mappedCitation-25992613 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/25992613 |
| http://purl.uniprot.org/uniprot/#_B5BU53-mappedCitation-25992613 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/25992613 |
| http://purl.uniprot.org/uniprot/#_D2WEZ3-mappedCitation-25992613 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/25992613 |
| http://purl.uniprot.org/uniprot/#_Q13560-mappedCitation-25992613 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/25992613 |
| http://purl.uniprot.org/uniprot/#_P50750-mappedCitation-25992613 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/25992613 |
| http://purl.uniprot.org/uniprot/#_Q04721-mappedCitation-25992613 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/25992613 |
| http://purl.uniprot.org/uniprot/#_Q6IQ50-mappedCitation-25992613 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/25992613 |
| http://purl.uniprot.org/uniprot/#_Q96JU8-mappedCitation-25992613 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/25992613 |
| http://purl.uniprot.org/uniprot/#_Q9UFD5-mappedCitation-25992613 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/25992613 |
| http://purl.uniprot.org/uniprot/Q9UFD5 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/25992613 |
| http://purl.uniprot.org/uniprot/Q04721 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/25992613 |
| http://purl.uniprot.org/uniprot/P50750 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/25992613 |