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http://purl.uniprot.org/citations/25999507http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/25999507http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/25999507http://www.w3.org/2000/01/rdf-schema#comment"Extremophiles, microorganisms thriving in extreme environmental conditions, must have proteins and nucleic acids that are stable at extremes of temperature and pH. The nonenveloped, rod-shaped virus SIRV2 (Sulfolobus islandicus rod-shaped virus 2) infects the hyperthermophilic acidophile Sulfolobus islandicus, which lives at 80°C and pH 3. We have used cryo-electron microscopy to generate a three-dimensional reconstruction of the SIRV2 virion at ~4 angstrom resolution, which revealed a previously unknown form of virion organization. Although almost half of the capsid protein is unstructured in solution, this unstructured region folds in the virion into a single extended α helix that wraps around the DNA. The DNA is entirely in the A-form, which suggests a common mechanism with bacterial spores for protecting DNA in the most adverse environments."xsd:string
http://purl.uniprot.org/citations/25999507http://purl.org/dc/terms/identifier"doi:10.1126/science.aaa4181"xsd:string
http://purl.uniprot.org/citations/25999507http://purl.org/dc/terms/identifier"doi:10.1126/science.aaa4181"xsd:string
http://purl.uniprot.org/citations/25999507http://purl.uniprot.org/core/author"Egelman E.H."xsd:string
http://purl.uniprot.org/citations/25999507http://purl.uniprot.org/core/author"Egelman E.H."xsd:string
http://purl.uniprot.org/citations/25999507http://purl.uniprot.org/core/author"Krupovic M."xsd:string
http://purl.uniprot.org/citations/25999507http://purl.uniprot.org/core/author"Krupovic M."xsd:string
http://purl.uniprot.org/citations/25999507http://purl.uniprot.org/core/author"DiMaio F."xsd:string
http://purl.uniprot.org/citations/25999507http://purl.uniprot.org/core/author"DiMaio F."xsd:string
http://purl.uniprot.org/citations/25999507http://purl.uniprot.org/core/author"Prangishvili D."xsd:string
http://purl.uniprot.org/citations/25999507http://purl.uniprot.org/core/author"Prangishvili D."xsd:string
http://purl.uniprot.org/citations/25999507http://purl.uniprot.org/core/author"Rensen E."xsd:string
http://purl.uniprot.org/citations/25999507http://purl.uniprot.org/core/author"Rensen E."xsd:string
http://purl.uniprot.org/citations/25999507http://purl.uniprot.org/core/author"Yu X."xsd:string
http://purl.uniprot.org/citations/25999507http://purl.uniprot.org/core/author"Yu X."xsd:string
http://purl.uniprot.org/citations/25999507http://purl.uniprot.org/core/date"2015"xsd:gYear
http://purl.uniprot.org/citations/25999507http://purl.uniprot.org/core/date"2015"xsd:gYear
http://purl.uniprot.org/citations/25999507http://purl.uniprot.org/core/name"Science"xsd:string
http://purl.uniprot.org/citations/25999507http://purl.uniprot.org/core/name"Science"xsd:string
http://purl.uniprot.org/citations/25999507http://purl.uniprot.org/core/pages"914-917"xsd:string
http://purl.uniprot.org/citations/25999507http://purl.uniprot.org/core/pages"914-917"xsd:string
http://purl.uniprot.org/citations/25999507http://purl.uniprot.org/core/title"Virology. A virus that infects a hyperthermophile encapsidates A-form DNA."xsd:string
http://purl.uniprot.org/citations/25999507http://purl.uniprot.org/core/title"Virology. A virus that infects a hyperthermophile encapsidates A-form DNA."xsd:string