| http://purl.uniprot.org/citations/2602386 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/2602386 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/2602386 | http://www.w3.org/2000/01/rdf-schema#comment | "A cDNA encoding the alpha subunit of mouse skeletal muscle phosphorylase kinase was used to compare the expression of alpha mRNAs in normal and phosphorylase kinase-deficient tissues of the I/Lyn mouse. The results demonstrate that two different molecular weight species of poly(A)+ RNA in normal mouse heart and skeletal muscle hybridize to the alpha cDNA. These two mRNAs direct the synthesis of alpha protein and its isoform alpha' in a cell-free translation system. Thus, alpha and alpha' are encoded by two distinct mRNAs. The abundance of both of these mRNAs is reduced dramatically in the phosphorylase kinase-deficient skeletal muscle and heart tissues from the I/Lyn mouse strain. This result indicates that a mechanism common to both alpha and alpha' expression is disrupted by the I/Lyn mutation. The I/Lyn deficiency is inherited as an X chromosome trait. By Southern mapping of Chinese hamster-mouse cell hybrids the alpha gene was localized to the mouse X chromosome, supporting the possibility that the I/Lyn mutation is in the alpha gene. These results are discussed in terms of a cis or trans mutation influencing the expression of either a single alpha/alpha' gene or two genes encoding alpha and alpha'."xsd:string |
| http://purl.uniprot.org/citations/2602386 | http://purl.org/dc/terms/identifier | "doi:10.1073/pnas.86.24.9996"xsd:string |
| http://purl.uniprot.org/citations/2602386 | http://purl.org/dc/terms/identifier | "doi:10.1073/pnas.86.24.9996"xsd:string |
| http://purl.uniprot.org/citations/2602386 | http://purl.uniprot.org/core/author | "Lalley P.A."xsd:string |
| http://purl.uniprot.org/citations/2602386 | http://purl.uniprot.org/core/author | "Lalley P.A."xsd:string |
| http://purl.uniprot.org/citations/2602386 | http://purl.uniprot.org/core/author | "Bender P.K."xsd:string |
| http://purl.uniprot.org/citations/2602386 | http://purl.uniprot.org/core/author | "Bender P.K."xsd:string |
| http://purl.uniprot.org/citations/2602386 | http://purl.uniprot.org/core/date | "1989"xsd:gYear |
| http://purl.uniprot.org/citations/2602386 | http://purl.uniprot.org/core/date | "1989"xsd:gYear |
| http://purl.uniprot.org/citations/2602386 | http://purl.uniprot.org/core/name | "Proc. Natl. Acad. Sci. U.S.A."xsd:string |
| http://purl.uniprot.org/citations/2602386 | http://purl.uniprot.org/core/name | "Proc. Natl. Acad. Sci. U.S.A."xsd:string |
| http://purl.uniprot.org/citations/2602386 | http://purl.uniprot.org/core/pages | "9996-10000"xsd:string |
| http://purl.uniprot.org/citations/2602386 | http://purl.uniprot.org/core/pages | "9996-10000"xsd:string |
| http://purl.uniprot.org/citations/2602386 | http://purl.uniprot.org/core/title | "I/Lyn mouse phosphorylase kinase deficiency: mutation disrupts expression of the alpha/alpha'-subunit mRNAs."xsd:string |
| http://purl.uniprot.org/citations/2602386 | http://purl.uniprot.org/core/title | "I/Lyn mouse phosphorylase kinase deficiency: mutation disrupts expression of the alpha/alpha'-subunit mRNAs."xsd:string |
| http://purl.uniprot.org/citations/2602386 | http://purl.uniprot.org/core/volume | "86"xsd:string |
| http://purl.uniprot.org/citations/2602386 | http://purl.uniprot.org/core/volume | "86"xsd:string |
| http://purl.uniprot.org/citations/2602386 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/2602386 |
| http://purl.uniprot.org/citations/2602386 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/2602386 |
| http://purl.uniprot.org/citations/2602386 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/2602386 |
| http://purl.uniprot.org/citations/2602386 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/2602386 |
| http://purl.uniprot.org/embl-cds/AAA39927.1 | http://purl.uniprot.org/core/citation | http://purl.uniprot.org/citations/2602386 |
| http://purl.uniprot.org/uniprot/P18826 | http://purl.uniprot.org/core/citation | http://purl.uniprot.org/citations/2602386 |