| http://purl.uniprot.org/citations/26040671 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/26040671 | http://www.w3.org/2000/01/rdf-schema#comment | "Uterine stromal cells undergo extensive proliferation and differentiation during postimplantation development, a process known as decidualization. While a range of signaling molecules have been demonstrated to play essential roles in this event, its potential epigenetic regulatory mechanisms remain largely unknown. Retinoblastoma binding protein 7 (Rbbp7) is a protein reported as a core component of many histone modification and chromatin remodeling complexes. In the present study, our in situ hybridization and immunochemistry analysis first reveals a spatiotemporal expression of Rbbp7 in the uterus during the peri-implantation period. Observations of remarkable induction of Rbbp7 expression in uterine stromal cells in response to progesterone-nuclear receptor PR signaling point to its potential physiological significance during postimplantation uterine development. Employing a stealth RNA knockdown approach, combined with primary murine uterine stromal cell culture and an in vitro-induced decidualization model, we further demonstrate that Rbbp7 silencing compromises stromal cell decidualization via attenuating histone H4 acetylation and cyclin D3 expression. The results collectively suggest that Rbbp7 is a potentially functional player regulating normal histone acetylation modification and cyclin D3 expression in stromal cells during postimplantation decidual development."xsd:string |
| http://purl.uniprot.org/citations/26040671 | http://purl.org/dc/terms/identifier | "doi:10.1095/biolreprod.115.129015"xsd:string |
| http://purl.uniprot.org/citations/26040671 | http://purl.uniprot.org/core/author | "He H."xsd:string |
| http://purl.uniprot.org/citations/26040671 | http://purl.uniprot.org/core/author | "Jiang Y."xsd:string |
| http://purl.uniprot.org/citations/26040671 | http://purl.uniprot.org/core/author | "Liu F."xsd:string |
| http://purl.uniprot.org/citations/26040671 | http://purl.uniprot.org/core/author | "Liao Y."xsd:string |
| http://purl.uniprot.org/citations/26040671 | http://purl.uniprot.org/core/author | "Li Q."xsd:string |
| http://purl.uniprot.org/citations/26040671 | http://purl.uniprot.org/core/author | "Jiang Y.'"xsd:string |
| http://purl.uniprot.org/citations/26040671 | http://purl.uniprot.org/core/author | "Zhou Z."xsd:string |
| http://purl.uniprot.org/citations/26040671 | http://purl.uniprot.org/core/author | "Zhang S."xsd:string |
| http://purl.uniprot.org/citations/26040671 | http://purl.uniprot.org/core/author | "Wang H."xsd:string |
| http://purl.uniprot.org/citations/26040671 | http://purl.uniprot.org/core/author | "Wang B."xsd:string |
| http://purl.uniprot.org/citations/26040671 | http://purl.uniprot.org/core/author | "Kong S."xsd:string |
| http://purl.uniprot.org/citations/26040671 | http://purl.uniprot.org/core/author | "Huo R."xsd:string |
| http://purl.uniprot.org/citations/26040671 | http://purl.uniprot.org/core/date | "2015"xsd:gYear |
| http://purl.uniprot.org/citations/26040671 | http://purl.uniprot.org/core/name | "Biol Reprod"xsd:string |
| http://purl.uniprot.org/citations/26040671 | http://purl.uniprot.org/core/pages | "13"xsd:string |
| http://purl.uniprot.org/citations/26040671 | http://purl.uniprot.org/core/title | "Rbbp7 Is Required for Uterine Stromal Decidualization in Mice."xsd:string |
| http://purl.uniprot.org/citations/26040671 | http://purl.uniprot.org/core/volume | "93"xsd:string |
| http://purl.uniprot.org/citations/26040671 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/26040671 |
| http://purl.uniprot.org/citations/26040671 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/26040671 |
| http://purl.uniprot.org/uniprot/#_A2AFI9-mappedCitation-26040671 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/26040671 |
| http://purl.uniprot.org/uniprot/#_A2AFJ1-mappedCitation-26040671 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/26040671 |
| http://purl.uniprot.org/uniprot/#_F6U539-mappedCitation-26040671 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/26040671 |