| http://purl.uniprot.org/citations/26071602 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/26071602 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/26071602 | http://www.w3.org/2000/01/rdf-schema#comment | "The composition of the mitochondrial membrane is important for its architecture and proper function. Mitochondria depend on a tightly regulated supply of phospholipid via intra-mitochondrial synthesis and by direct import from the endoplasmic reticulum. The Ups1/PRELI-like family together with its mitochondrial chaperones (TRIAP1/Mdm35) represent a unique heterodimeric lipid transfer system that is evolutionary conserved from yeast to man. Work presented here provides new atomic resolution insight into the function of a human member of this system. Crystal structures of free TRIAP1 and the TRIAP1-SLMO1 complex reveal how the PRELI domain is chaperoned during import into the intermembrane mitochondrial space. The structural resemblance of PRELI-like domain of SLMO1 with that of mammalian phoshatidylinositol transfer proteins (PITPs) suggest that they share similar lipid transfer mechanisms, in which access to a buried phospholipid-binding cavity is regulated by conformationally adaptable loops."xsd:string |
| http://purl.uniprot.org/citations/26071602 | http://purl.org/dc/terms/identifier | "doi:10.15252/embr.201540229"xsd:string |
| http://purl.uniprot.org/citations/26071602 | http://purl.org/dc/terms/identifier | "doi:10.15252/embr.201540229"xsd:string |
| http://purl.uniprot.org/citations/26071602 | http://purl.uniprot.org/core/author | "Matthews S."xsd:string |
| http://purl.uniprot.org/citations/26071602 | http://purl.uniprot.org/core/author | "Matthews S."xsd:string |
| http://purl.uniprot.org/citations/26071602 | http://purl.uniprot.org/core/author | "Simpson P."xsd:string |
| http://purl.uniprot.org/citations/26071602 | http://purl.uniprot.org/core/author | "Simpson P."xsd:string |
| http://purl.uniprot.org/citations/26071602 | http://purl.uniprot.org/core/author | "Langer T."xsd:string |
| http://purl.uniprot.org/citations/26071602 | http://purl.uniprot.org/core/author | "Langer T."xsd:string |
| http://purl.uniprot.org/citations/26071602 | http://purl.uniprot.org/core/author | "Garnett J.A."xsd:string |
| http://purl.uniprot.org/citations/26071602 | http://purl.uniprot.org/core/author | "Garnett J.A."xsd:string |
| http://purl.uniprot.org/citations/26071602 | http://purl.uniprot.org/core/author | "Perez-Dorado I."xsd:string |
| http://purl.uniprot.org/citations/26071602 | http://purl.uniprot.org/core/author | "Perez-Dorado I."xsd:string |
| http://purl.uniprot.org/citations/26071602 | http://purl.uniprot.org/core/author | "Tatsuta T."xsd:string |
| http://purl.uniprot.org/citations/26071602 | http://purl.uniprot.org/core/author | "Tatsuta T."xsd:string |
| http://purl.uniprot.org/citations/26071602 | http://purl.uniprot.org/core/author | "Yague E."xsd:string |
| http://purl.uniprot.org/citations/26071602 | http://purl.uniprot.org/core/author | "Yague E."xsd:string |
| http://purl.uniprot.org/citations/26071602 | http://purl.uniprot.org/core/author | "Abid Ali F."xsd:string |
| http://purl.uniprot.org/citations/26071602 | http://purl.uniprot.org/core/author | "Abid Ali F."xsd:string |
| http://purl.uniprot.org/citations/26071602 | http://purl.uniprot.org/core/author | "Baldie H."xsd:string |
| http://purl.uniprot.org/citations/26071602 | http://purl.uniprot.org/core/author | "Baldie H."xsd:string |
| http://purl.uniprot.org/citations/26071602 | http://purl.uniprot.org/core/author | "Miliara X."xsd:string |
| http://purl.uniprot.org/citations/26071602 | http://purl.uniprot.org/core/author | "Miliara X."xsd:string |