| http://purl.uniprot.org/citations/26077951 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/26077951 | http://www.w3.org/2000/01/rdf-schema#comment | "Corticobasal degeneration (CBD) is a neurodegenerative disorder affecting movement and cognition, definitively diagnosed only at autopsy. Here, we conduct a genome-wide association study (GWAS) in CBD cases (n=152) and 3,311 controls, and 67 CBD cases and 439 controls in a replication stage. Associations with meta-analysis were 17q21 at MAPT (P=1.42 × 10(-12)), 8p12 at lnc-KIF13B-1, a long non-coding RNA (rs643472; P=3.41 × 10(-8)), and 2p22 at SOS1 (rs963731; P=1.76 × 10(-7)). Testing for association of CBD with top progressive supranuclear palsy (PSP) GWAS single-nucleotide polymorphisms (SNPs) identified associations at MOBP (3p22; rs1768208; P=2.07 × 10(-7)) and MAPT H1c (17q21; rs242557; P=7.91 × 10(-6)). We previously reported SNP/transcript level associations with rs8070723/MAPT, rs242557/MAPT, and rs1768208/MOBP and herein identified association with rs963731/SOS1. We identify new CBD susceptibility loci and show that CBD and PSP share a genetic risk factor other than MAPT at 3p22 MOBP (myelin-associated oligodendrocyte basic protein)."xsd:string |
| http://purl.uniprot.org/citations/26077951 | http://purl.org/dc/terms/identifier | "doi:10.1038/ncomms8247"xsd:string |
| http://purl.uniprot.org/citations/26077951 | http://purl.uniprot.org/core/author | "Devlin B."xsd:string |
| http://purl.uniprot.org/citations/26077951 | http://purl.uniprot.org/core/author | "Kim J."xsd:string |
| http://purl.uniprot.org/citations/26077951 | http://purl.uniprot.org/core/author | "Fujioka S."xsd:string |
| http://purl.uniprot.org/citations/26077951 | http://purl.uniprot.org/core/author | "Baker M."xsd:string |
| http://purl.uniprot.org/citations/26077951 | http://purl.uniprot.org/core/author | "Boeve B.F."xsd:string |
| http://purl.uniprot.org/citations/26077951 | http://purl.uniprot.org/core/author | "Dickson D.W."xsd:string |
| http://purl.uniprot.org/citations/26077951 | http://purl.uniprot.org/core/author | "Ghetti B."xsd:string |
| http://purl.uniprot.org/citations/26077951 | http://purl.uniprot.org/core/author | "Kouri N."xsd:string |
| http://purl.uniprot.org/citations/26077951 | http://purl.uniprot.org/core/author | "Kretzschmar H.A."xsd:string |
| http://purl.uniprot.org/citations/26077951 | http://purl.uniprot.org/core/author | "Rademakers R."xsd:string |
| http://purl.uniprot.org/citations/26077951 | http://purl.uniprot.org/core/author | "Roeber S."xsd:string |
| http://purl.uniprot.org/citations/26077951 | http://purl.uniprot.org/core/author | "Ross O.A."xsd:string |
| http://purl.uniprot.org/citations/26077951 | http://purl.uniprot.org/core/author | "Soto-Ortolaza A."xsd:string |
| http://purl.uniprot.org/citations/26077951 | http://purl.uniprot.org/core/author | "Spina S."xsd:string |
| http://purl.uniprot.org/citations/26077951 | http://purl.uniprot.org/core/author | "Wszolek Z.K."xsd:string |
| http://purl.uniprot.org/citations/26077951 | http://purl.uniprot.org/core/author | "Farlow M.R."xsd:string |
| http://purl.uniprot.org/citations/26077951 | http://purl.uniprot.org/core/author | "Schellenberg G.D."xsd:string |
| http://purl.uniprot.org/citations/26077951 | http://purl.uniprot.org/core/author | "Vonsattel J.P.G."xsd:string |
| http://purl.uniprot.org/citations/26077951 | http://purl.uniprot.org/core/author | "Younkin S.G."xsd:string |
| http://purl.uniprot.org/citations/26077951 | http://purl.uniprot.org/core/author | "Gearing M."xsd:string |
| http://purl.uniprot.org/citations/26077951 | http://purl.uniprot.org/core/author | "White C.L."xsd:string |
| http://purl.uniprot.org/citations/26077951 | http://purl.uniprot.org/core/author | "Parisi J.E."xsd:string |