| http://purl.uniprot.org/citations/26102503 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/26102503 | http://www.w3.org/2000/01/rdf-schema#comment | "Phototropic regulation of circadian clock is important for environmental adaptation, organismal growth and differentiation. Light plays a critical role in fungal development and virulence. However, it is unclear what governs the intracellular metabolic response to such dark-light rhythms in fungi. Here, we describe a novel circadian-regulated Twilight (TWL) function essential for phototropic induction of asexual development and pathogenesis in the rice-blast fungus Magnaporthe oryzae. The TWL transcript oscillates during circadian cycles and peaks at subjective twilight. GFP-Twl remains acetylated and cytosolic in the dark, whereas light-induced phosphorylation (by the carbon sensor Snf1 kinase) drives it into the nucleus. The mRNA level of the transcription/repair factor TFB5, was significantly down regulated in the twl∆ mutant. Overexpression of TFB5 significantly suppressed the conidiation defects in the twl∆ mutant. Furthermore, Tfb5-GFP translocates to the nucleus during the phototropic response and under redox stress, while it failed to do so in the twl∆ mutant. Thus, we provide mechanistic insight into Twl-based regulation of nutrient and redox homeostasis in response to light during pathogen adaptation to the host milieu in the rice blast pathosystem."xsd:string |
| http://purl.uniprot.org/citations/26102503 | http://purl.org/dc/terms/identifier | "doi:10.1371/journal.ppat.1004972"xsd:string |
| http://purl.uniprot.org/citations/26102503 | http://purl.uniprot.org/core/author | "Naqvi N.I."xsd:string |
| http://purl.uniprot.org/citations/26102503 | http://purl.uniprot.org/core/author | "Qu Z."xsd:string |
| http://purl.uniprot.org/citations/26102503 | http://purl.uniprot.org/core/author | "Deng Y.Z."xsd:string |
| http://purl.uniprot.org/citations/26102503 | http://purl.uniprot.org/core/date | "2015"xsd:gYear |
| http://purl.uniprot.org/citations/26102503 | http://purl.uniprot.org/core/name | "PLoS Pathog"xsd:string |
| http://purl.uniprot.org/citations/26102503 | http://purl.uniprot.org/core/pages | "e1004972"xsd:string |
| http://purl.uniprot.org/citations/26102503 | http://purl.uniprot.org/core/title | "Twilight, a Novel Circadian-Regulated Gene, Integrates Phototropism with Nutrient and Redox Homeostasis during Fungal Development."xsd:string |
| http://purl.uniprot.org/citations/26102503 | http://purl.uniprot.org/core/volume | "11"xsd:string |
| http://purl.uniprot.org/citations/26102503 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/26102503 |
| http://purl.uniprot.org/citations/26102503 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/26102503 |
| http://purl.uniprot.org/uniprot/#_Q9FE01-mappedCitation-26102503 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/26102503 |
| http://purl.uniprot.org/uniprot/Q9FE01 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/26102503 |