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http://purl.uniprot.org/citations/26119197http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/26119197http://www.w3.org/2000/01/rdf-schema#comment"

Background

Cholecystitis is one of the major digestive diseases. Its prevalence is particularly high in some populations. Significant risk factors associated with cholecystitis include age, sex, obesity, diet, parity and type 2 diabetes.

Objective

To determine the association between HLA-DRB1 and cholecystitis.

Methods

This case-control study included forty Iraqi Arab patients who had cholecystitis with multiple calculi treated by cholecystectomy admitted in the surgical ward at Al-Kindy Teaching Hospital Baghdad between September -2013 to June -2014. The control group consisted of forty healthy volunteers among the staff of Al-Kindy College of Medicine. Control and cholecystitis patients groups were typed for identifying the DRB1* alleles using DNA-based methodology (PCR-SSOP).

Results

There was an increased frequency of HLA-DRB1*0301 in patients with cholecystitis compared with healthy controls (p=0.0442, odd ratio=4.1111, 95% CI: 1.0372-16.2949).

Conclusion

HLA-DRB1*0301, as a genetic factor, seems to have an association with cholecystitis."xsd:string
http://purl.uniprot.org/citations/26119197http://purl.uniprot.org/core/author"Abid L.A."xsd:string
http://purl.uniprot.org/citations/26119197http://purl.uniprot.org/core/author"Al-Marzook T.J."xsd:string
http://purl.uniprot.org/citations/26119197http://purl.uniprot.org/core/author"Mutar Mahdi B."xsd:string
http://purl.uniprot.org/citations/26119197http://purl.uniprot.org/core/author"Nehad Z."xsd:string
http://purl.uniprot.org/citations/26119197http://purl.uniprot.org/core/author"Raouf H."xsd:string
http://purl.uniprot.org/citations/26119197http://purl.uniprot.org/core/author"Zalzala H.H."xsd:string
http://purl.uniprot.org/citations/26119197http://purl.uniprot.org/core/date"2015"xsd:gYear
http://purl.uniprot.org/citations/26119197http://purl.uniprot.org/core/name"Iran J Immunol"xsd:string
http://purl.uniprot.org/citations/26119197http://purl.uniprot.org/core/pages"149-155"xsd:string
http://purl.uniprot.org/citations/26119197http://purl.uniprot.org/core/title"The Effect of HLA-DRB1 on Cholecystitis."xsd:string
http://purl.uniprot.org/citations/26119197http://purl.uniprot.org/core/volume"12"xsd:string
http://purl.uniprot.org/citations/26119197http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/26119197
http://purl.uniprot.org/citations/26119197http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/26119197
http://purl.uniprot.org/uniprot/#_A0A0A7C3H3-mappedCitation-26119197http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/26119197
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http://purl.uniprot.org/uniprot/#_A0A141AZI1-mappedCitation-26119197http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/26119197
http://purl.uniprot.org/uniprot/#_A0A141AZI3-mappedCitation-26119197http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/26119197
http://purl.uniprot.org/uniprot/#_A0A141AZI4-mappedCitation-26119197http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/26119197
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