| http://purl.uniprot.org/citations/26129648 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/26129648 | http://www.w3.org/2000/01/rdf-schema#comment | "Group 2 innate lymphoid cells (ILC2s) have an important role in acute allergic lung inflammation. Given their distribution and function, lung ILC2s are hypothesized to coordinate epithelial responses to the external environment; however, how barrier surveillance is linked to ILC2 activation remains unclear. Here, we demonstrate that alveolar type II cells are the main source of interleukin (IL)-33 and thymic stromal lymphopoietin (TSLP) generated in response to chitin or migratory helminths. IL-33 and TSLP synergistically induce an interferon regulatory factor 4 (IRF4)-IL-9 program in ILC2s, and autocrine IL-9 promotes rapid IL-5 and IL-13 production required for optimal epithelial responses in the conducting airways. Thus, ILC2s link alveolar function to regulation of airway flow, revealing a key interaction between resident lymphoid and structural cells that might underlie similar organizational hierarchies in other organs."xsd:string |
| http://purl.uniprot.org/citations/26129648 | http://purl.org/dc/terms/identifier | "doi:10.1038/mi.2015.59"xsd:string |
| http://purl.uniprot.org/citations/26129648 | http://purl.uniprot.org/core/author | "Schneider C."xsd:string |
| http://purl.uniprot.org/citations/26129648 | http://purl.uniprot.org/core/author | "Locksley R.M."xsd:string |
| http://purl.uniprot.org/citations/26129648 | http://purl.uniprot.org/core/author | "Nussbaum J.C."xsd:string |
| http://purl.uniprot.org/citations/26129648 | http://purl.uniprot.org/core/author | "Mohapatra A."xsd:string |
| http://purl.uniprot.org/citations/26129648 | http://purl.uniprot.org/core/author | "Liang H.E."xsd:string |
| http://purl.uniprot.org/citations/26129648 | http://purl.uniprot.org/core/author | "Van Dyken S.J."xsd:string |
| http://purl.uniprot.org/citations/26129648 | http://purl.uniprot.org/core/date | "2016"xsd:gYear |
| http://purl.uniprot.org/citations/26129648 | http://purl.uniprot.org/core/name | "Mucosal Immunol"xsd:string |
| http://purl.uniprot.org/citations/26129648 | http://purl.uniprot.org/core/pages | "275-286"xsd:string |
| http://purl.uniprot.org/citations/26129648 | http://purl.uniprot.org/core/title | "Group 2 innate lymphoid cells utilize the IRF4-IL-9 module to coordinate epithelial cell maintenance of lung homeostasis."xsd:string |
| http://purl.uniprot.org/citations/26129648 | http://purl.uniprot.org/core/volume | "9"xsd:string |
| http://purl.uniprot.org/citations/26129648 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/26129648 |
| http://purl.uniprot.org/citations/26129648 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/26129648 |
| http://purl.uniprot.org/uniprot/#_A0A0G2JGP1-mappedCitation-26129648 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/26129648 |
| http://purl.uniprot.org/uniprot/#_A0A0R4J0F5-mappedCitation-26129648 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/26129648 |
| http://purl.uniprot.org/uniprot/#_A0A0G2JF13-mappedCitation-26129648 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/26129648 |
| http://purl.uniprot.org/uniprot/#_A0A1Y7VIT1-mappedCitation-26129648 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/26129648 |
| http://purl.uniprot.org/uniprot/#_D3Z6T7-mappedCitation-26129648 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/26129648 |
| http://purl.uniprot.org/uniprot/#_G3UYU3-mappedCitation-26129648 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/26129648 |
| http://purl.uniprot.org/uniprot/#_E9M2E8-mappedCitation-26129648 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/26129648 |
| http://purl.uniprot.org/uniprot/#_H3BLN5-mappedCitation-26129648 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/26129648 |
| http://purl.uniprot.org/uniprot/#_Q62349-mappedCitation-26129648 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/26129648 |