| http://purl.uniprot.org/citations/26188085 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/26188085 | http://www.w3.org/2000/01/rdf-schema#comment | "Many published case-control studies have investigated the association between rs12456492(A/G) variant in RIT2 gene and the risk of Parkinson's disease(PD); however, an ambiguous conclusion remains elusive. Our aim was to evaluate the association of RIT2 rs12456492(A/G) polymorphism with the risk of PD. We searched the Pubmed, Science Direct, EMBASE and EBSCO databases up to May 2015 for related studies. A total of 5 studies with 2541 PD cases and 2531 controls were included in the meta-analysis based on the strict inclusion and exclusion criteria. STATA 12.0 statistics software was used to calculate available data from each study. The pooled odds ratios (OR) and 95% confidence interval (CI) were calculated to assess the genetic association between RIT2 rs12456492 polymorphism and the risk of PD. There is a significant association between rs12456492 and PD (Gvs.A:OR=1.024, 95%CI:1.112-1.303, P=0.001; GGvs.AA:OR=1.486, 95%CI:1.259-1.755, P=0.001; GAvs.AA:OR=1.217, 95%CI:1.071-1.383, P=0.003; GG+GAvs.AA:OR=1.290, 95%CI:1.143-1.455, P=0.001; GGvs.GA+AA:OR=1.262, 95%CI:1.097-1.451, P=0.001). The data of our meta-analysis indicates that the G allele, GG and GA genotype of rs12456492(A/G) polymorphism may increase the risk of PD."xsd:string |
| http://purl.uniprot.org/citations/26188085 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.neulet.2015.07.004"xsd:string |
| http://purl.uniprot.org/citations/26188085 | http://purl.uniprot.org/core/author | "Li H."xsd:string |
| http://purl.uniprot.org/citations/26188085 | http://purl.uniprot.org/core/author | "Niu M."xsd:string |
| http://purl.uniprot.org/citations/26188085 | http://purl.uniprot.org/core/author | "Zhang X."xsd:string |
| http://purl.uniprot.org/citations/26188085 | http://purl.uniprot.org/core/author | "Xie A."xsd:string |
| http://purl.uniprot.org/citations/26188085 | http://purl.uniprot.org/core/date | "2015"xsd:gYear |
| http://purl.uniprot.org/citations/26188085 | http://purl.uniprot.org/core/name | "Neurosci Lett"xsd:string |
| http://purl.uniprot.org/citations/26188085 | http://purl.uniprot.org/core/pages | "167-171"xsd:string |
| http://purl.uniprot.org/citations/26188085 | http://purl.uniprot.org/core/title | "RIT2 rs12456492 polymorphism and the risk of Parkinson's disease: A meta-analysis."xsd:string |
| http://purl.uniprot.org/citations/26188085 | http://purl.uniprot.org/core/volume | "602"xsd:string |
| http://purl.uniprot.org/citations/26188085 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/26188085 |
| http://purl.uniprot.org/citations/26188085 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/26188085 |
| http://purl.uniprot.org/uniprot/#_Q99578-mappedCitation-26188085 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/26188085 |
| http://purl.uniprot.org/uniprot/Q99578 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/26188085 |