| http://purl.uniprot.org/citations/26193421 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/26193421 | http://www.w3.org/2000/01/rdf-schema#comment | "S100P signaling through the receptor for advanced glycation end-products (RAGE) contributes to colon cancer invasion and metastasis, but the mechanistic features of this process are obscure. Here, we investigate whether activation of S100P/RAGE signaling regulates oncogenic microRNA-21 (miR-21). We show that exogenous S100P up-regulates miR-21 levels in human colon cancer cells, whereas knockdown of S100P results in a decrease of miR-21. Furthermore, blockage of RAGE with anti-RAGE antibody suppresses S100P induction of miR-21. In addition, we found that S100P induction of miR-21 expression involves ERK and is suppressed by the MEK inhibitor U0126. Also, S100P treatment stimulates the enrichment of c-Fos, and AP-1 family members, at the miR-21 gene promoter."xsd:string |
| http://purl.uniprot.org/citations/26193421 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.febslet.2015.07.010"xsd:string |
| http://purl.uniprot.org/citations/26193421 | http://purl.uniprot.org/core/author | "Li Q."xsd:string |
| http://purl.uniprot.org/citations/26193421 | http://purl.uniprot.org/core/author | "Nelson M.A."xsd:string |
| http://purl.uniprot.org/citations/26193421 | http://purl.uniprot.org/core/author | "Pimentel A.C."xsd:string |
| http://purl.uniprot.org/citations/26193421 | http://purl.uniprot.org/core/author | "Jandova J."xsd:string |
| http://purl.uniprot.org/citations/26193421 | http://purl.uniprot.org/core/author | "Mercado-Pimentel M.E."xsd:string |
| http://purl.uniprot.org/citations/26193421 | http://purl.uniprot.org/core/author | "Onyeagucha B.C."xsd:string |
| http://purl.uniprot.org/citations/26193421 | http://purl.uniprot.org/core/date | "2015"xsd:gYear |
| http://purl.uniprot.org/citations/26193421 | http://purl.uniprot.org/core/name | "FEBS Lett"xsd:string |
| http://purl.uniprot.org/citations/26193421 | http://purl.uniprot.org/core/pages | "2388-2393"xsd:string |
| http://purl.uniprot.org/citations/26193421 | http://purl.uniprot.org/core/title | "The S100P/RAGE signaling pathway regulates expression of microRNA-21 in colon cancer cells."xsd:string |
| http://purl.uniprot.org/citations/26193421 | http://purl.uniprot.org/core/volume | "589"xsd:string |
| http://purl.uniprot.org/citations/26193421 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/26193421 |
| http://purl.uniprot.org/citations/26193421 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/26193421 |
| http://purl.uniprot.org/uniprot/#_E9LVY5-mappedCitation-26193421 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/26193421 |
| http://purl.uniprot.org/uniprot/#_E9LVY6-mappedCitation-26193421 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/26193421 |
| http://purl.uniprot.org/uniprot/#_E9LVY7-mappedCitation-26193421 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/26193421 |
| http://purl.uniprot.org/uniprot/#_F1ABM9-mappedCitation-26193421 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/26193421 |
| http://purl.uniprot.org/uniprot/#_F1ABN0-mappedCitation-26193421 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/26193421 |
| http://purl.uniprot.org/uniprot/#_F1ABN1-mappedCitation-26193421 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/26193421 |
| http://purl.uniprot.org/uniprot/#_Q15109-mappedCitation-26193421 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/26193421 |
| http://purl.uniprot.org/uniprot/#_A0A1U9X782-mappedCitation-26193421 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/26193421 |
| http://purl.uniprot.org/uniprot/#_A0A1U9X785-mappedCitation-26193421 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/26193421 |