| http://purl.uniprot.org/citations/26199285 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/26199285 | http://www.w3.org/2000/01/rdf-schema#comment | "RNA binding proteins (RBPs) are involved in many cellular functions. To facilitate functional characterization of RBPs, we generated an RNA interference (RNAi) library for Drosophila cell-based screens comprising reagents targeting known or putative RBPs. To test the quality of the library and provide a baseline analysis of the effects of the RNAi reagents on viability, we screened the library using a total ATP assay and high-throughput imaging in Drosophila S2R+ cultured cells. The results are consistent with production of a high-quality library that will be useful for functional genomics studies using other assays. Altogether, we provide resources in the form of an initial curated list of Drosophila RBPs; an RNAi screening library we expect to be used with additional assays that address more specific biological questions; and total ATP and image data useful for comparison of those additional assay results with fundamental information such as effects of a given reagent in the library on cell viability. Importantly, we make the baseline data, including more than 200,000 images, easily accessible online."xsd:string |
| http://purl.uniprot.org/citations/26199285 | http://purl.org/dc/terms/identifier | "doi:10.1534/g3.115.019364"xsd:string |
| http://purl.uniprot.org/citations/26199285 | http://purl.uniprot.org/core/author | "Foster B."xsd:string |
| http://purl.uniprot.org/citations/26199285 | http://purl.uniprot.org/core/author | "Hu Y."xsd:string |
| http://purl.uniprot.org/citations/26199285 | http://purl.uniprot.org/core/author | "Perrimon N."xsd:string |
| http://purl.uniprot.org/citations/26199285 | http://purl.uniprot.org/core/author | "Ye B."xsd:string |
| http://purl.uniprot.org/citations/26199285 | http://purl.uniprot.org/core/author | "Rudd K."xsd:string |
| http://purl.uniprot.org/citations/26199285 | http://purl.uniprot.org/core/author | "Mohr S.E."xsd:string |
| http://purl.uniprot.org/citations/26199285 | http://purl.uniprot.org/core/author | "Buckner M."xsd:string |
| http://purl.uniprot.org/citations/26199285 | http://purl.uniprot.org/core/author | "Comjean A."xsd:string |
| http://purl.uniprot.org/citations/26199285 | http://purl.uniprot.org/core/author | "Gilly Q."xsd:string |
| http://purl.uniprot.org/citations/26199285 | http://purl.uniprot.org/core/author | "Sierzputowska K."xsd:string |
| http://purl.uniprot.org/citations/26199285 | http://purl.uniprot.org/core/date | "2015"xsd:gYear |
| http://purl.uniprot.org/citations/26199285 | http://purl.uniprot.org/core/name | "G3 (Bethesda)"xsd:string |
| http://purl.uniprot.org/citations/26199285 | http://purl.uniprot.org/core/pages | "1919-1924"xsd:string |
| http://purl.uniprot.org/citations/26199285 | http://purl.uniprot.org/core/title | "Reagent and Data Resources for Investigation of RNA Binding Protein Functions in Drosophila melanogaster Cultured Cells."xsd:string |
| http://purl.uniprot.org/citations/26199285 | http://purl.uniprot.org/core/volume | "5"xsd:string |
| http://purl.uniprot.org/citations/26199285 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/26199285 |
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| http://purl.uniprot.org/uniprot/#_A0A0B4LFE6-mappedCitation-26199285 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/26199285 |
| http://purl.uniprot.org/uniprot/#_A0A0B4LFF9-mappedCitation-26199285 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/26199285 |