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http://purl.uniprot.org/citations/26204120http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/26204120http://www.w3.org/2000/01/rdf-schema#comment"Guillain-Barré syndrome (GBS) is an autoimmune disorder of the peripheral nervous system. There is no consensus regarding reported associations between human leukocyte antigen DQB1 (HLA-DQB1) polymorphisms and the risk for developing GBS. Here, we evaluated possible associations between HLA-DQB1 polymorphisms and the risk for GBS using a meta-analysis. We searched PubMed for case-control genetic association studies for HLA-DQB1 polymorphisms (*020x, *030x, *040x, *050x, and *060x) and the risk for GBS. Fixed-effect meta-analytical methods were used for the outcome measure and subgroup analyses. Estimated odds ratios (ORs) and 95% confidence intervals (CIs) were used to investigate the associations between HLA-DQB1 polymorphisms and the risk for GBS. Nine case-control studies involving 780 cases of GBS and 1353 controls were identified in the current study. The meta-analysis demonstrated no significant associations between HLA-DQB1 polymorphisms and the risk for GBS in Asian and Caucasian populations. There were two associations that approached significance: HLA-DQB1*030x in Asian patients (P = 0.07; OR: 0.76, 95% CI: 0.57-1.03) and HLA-DQB1*060x in all patients (P = 0.08; OR: 1.48, 95% CI: 0.96-2.29). Additional studies with larger sample sizes are required to establish a definitive assessment of the contribution of HLA-DQB1 polymorphisms to GBS risk."xsd:string
http://purl.uniprot.org/citations/26204120http://purl.org/dc/terms/identifier"doi:10.1371/journal.pone.0131374"xsd:string
http://purl.uniprot.org/citations/26204120http://purl.uniprot.org/core/author"Li L."xsd:string
http://purl.uniprot.org/citations/26204120http://purl.uniprot.org/core/author"Liu L.J."xsd:string
http://purl.uniprot.org/citations/26204120http://purl.uniprot.org/core/author"Zhao G."xsd:string
http://purl.uniprot.org/citations/26204120http://purl.uniprot.org/core/author"Wang W."xsd:string
http://purl.uniprot.org/citations/26204120http://purl.uniprot.org/core/author"Zhou B."xsd:string
http://purl.uniprot.org/citations/26204120http://purl.uniprot.org/core/author"Xia F."xsd:string
http://purl.uniprot.org/citations/26204120http://purl.uniprot.org/core/author"Sun L.L."xsd:string
http://purl.uniprot.org/citations/26204120http://purl.uniprot.org/core/author"Ding B.J."xsd:string
http://purl.uniprot.org/citations/26204120http://purl.uniprot.org/core/author"Qin N."xsd:string
http://purl.uniprot.org/citations/26204120http://purl.uniprot.org/core/author"Hou S.X."xsd:string
http://purl.uniprot.org/citations/26204120http://purl.uniprot.org/core/author"Liu X.D."xsd:string
http://purl.uniprot.org/citations/26204120http://purl.uniprot.org/core/author"Deng Y.C."xsd:string
http://purl.uniprot.org/citations/26204120http://purl.uniprot.org/core/author"Jin P.P."xsd:string
http://purl.uniprot.org/citations/26204120http://purl.uniprot.org/core/date"2015"xsd:gYear
http://purl.uniprot.org/citations/26204120http://purl.uniprot.org/core/name"PLoS One"xsd:string
http://purl.uniprot.org/citations/26204120http://purl.uniprot.org/core/pages"e0131374"xsd:string
http://purl.uniprot.org/citations/26204120http://purl.uniprot.org/core/title"Human Leukocyte Antigen DQB1 (HLA-DQB1) Polymorphisms and the Risk for Guillain-Barre Syndrome: A Systematic Review and Meta-Analysis."xsd:string
http://purl.uniprot.org/citations/26204120http://purl.uniprot.org/core/volume"10"xsd:string
http://purl.uniprot.org/citations/26204120http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/26204120
http://purl.uniprot.org/citations/26204120http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/26204120
http://purl.uniprot.org/uniprot/#_A0A0E3DC97-mappedCitation-26204120http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/26204120
http://purl.uniprot.org/uniprot/#_A0A0E3DC99-mappedCitation-26204120http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/26204120