| http://purl.uniprot.org/citations/26231763 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/26231763 | http://www.w3.org/2000/01/rdf-schema#comment | "O-Linked N-acetylglucosamine transferase (OGT) was identified as an Nrf1-interacting protein. Herein, we show that Nrf1 enables interaction with OGT and their co-immunoprecipitates are O-GlcNAcylated by the enzyme. The putative O-GlcNAcylation negatively regulates Nrf1/TCF11 to reduce both its protein stability and transactivation activity of target gene expression. The turnover of Nrf1 is enhanced upon overexpression of OGT, which promotes ubiquitination of the CNC-bZIP protein. Furthermore, the serine/theorine-rich sequence of PEST2 degron within Nrf1 is identified to be involved in the protein O-GlcNAcylation by OGT. Overall, Nrf1 is negatively regulated by its O-GlcNAcylation status that depends on the glucose concentrations."xsd:string |
| http://purl.uniprot.org/citations/26231763 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.febslet.2015.07.030"xsd:string |
| http://purl.uniprot.org/citations/26231763 | http://purl.uniprot.org/core/author | "Chen J."xsd:string |
| http://purl.uniprot.org/citations/26231763 | http://purl.uniprot.org/core/author | "Liu X."xsd:string |
| http://purl.uniprot.org/citations/26231763 | http://purl.uniprot.org/core/author | "Lu F."xsd:string |
| http://purl.uniprot.org/citations/26231763 | http://purl.uniprot.org/core/author | "Ren Y."xsd:string |
| http://purl.uniprot.org/citations/26231763 | http://purl.uniprot.org/core/author | "Zhang Y."xsd:string |
| http://purl.uniprot.org/citations/26231763 | http://purl.uniprot.org/core/author | "Ru Y."xsd:string |
| http://purl.uniprot.org/citations/26231763 | http://purl.uniprot.org/core/author | "Liu X.'"xsd:string |
| http://purl.uniprot.org/citations/26231763 | http://purl.uniprot.org/core/author | "Yao L."xsd:string |
| http://purl.uniprot.org/citations/26231763 | http://purl.uniprot.org/core/date | "2015"xsd:gYear |
| http://purl.uniprot.org/citations/26231763 | http://purl.uniprot.org/core/name | "FEBS Lett"xsd:string |
| http://purl.uniprot.org/citations/26231763 | http://purl.uniprot.org/core/pages | "2347-2358"xsd:string |
| http://purl.uniprot.org/citations/26231763 | http://purl.uniprot.org/core/title | "Transcription factor Nrf1 is negatively regulated by its O-GlcNAcylation status."xsd:string |
| http://purl.uniprot.org/citations/26231763 | http://purl.uniprot.org/core/volume | "589"xsd:string |
| http://purl.uniprot.org/citations/26231763 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/26231763 |
| http://purl.uniprot.org/citations/26231763 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/26231763 |
| http://purl.uniprot.org/uniprot/#_A0A0G2K3V4-mappedCitation-26231763 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/26231763 |
| http://purl.uniprot.org/uniprot/#_A0A0J9YU17-mappedCitation-26231763 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/26231763 |
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| http://purl.uniprot.org/uniprot/#_P56558-mappedCitation-26231763 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/26231763 |
| http://purl.uniprot.org/uniprot/#_A2A6D0-mappedCitation-26231763 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/26231763 |
| http://purl.uniprot.org/uniprot/#_A2A6D1-mappedCitation-26231763 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/26231763 |
| http://purl.uniprot.org/uniprot/#_A2A6D2-mappedCitation-26231763 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/26231763 |