| http://purl.uniprot.org/citations/26239416 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/26239416 | http://www.w3.org/2000/01/rdf-schema#comment | "Interleukin-23 (IL-23) and IL-17 are involved in the pathogenesis of allergic rhinitis (AR). However, the roles of IL-23 and IL-17 in ovalbumin (OVA)-induced AR remain unclear. Therefore in this study we aim to investigate the precise roles of IL-23 and IL-17 in a mouse model of OVA-induced AR. We found that during OVA-induced AR, eosinophil and goblet cells in the nose were significantly decreased in IL-23-deficient, but not in IL-17-deficient mice. However, there was no difference in the serum IgE and IgG1 levels between IL-23-deficient or IL-17-deficient and wild-type mice. Moreover, IL-4 levels in lymph node cell culture supernatants were significantly decreased in IL-23-deficient, but not IL-17-deficient, compared with wild-type mice. Furthermore, OVA-induced AR developed similarly in wild-type mice transferred with either IL-23-deficient BM cells or wild-type BM cells. These findings suggest that IL-23, but not IL-17 is crucial for the development of OVA-induced AR, and IL-23 neutralization may be a potential approach for treatment of OVA-induced AR in humans."xsd:string |
| http://purl.uniprot.org/citations/26239416 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.molimm.2015.07.009"xsd:string |
| http://purl.uniprot.org/citations/26239416 | http://purl.uniprot.org/core/author | "Chen G."xsd:string |
| http://purl.uniprot.org/citations/26239416 | http://purl.uniprot.org/core/author | "Guo C."xsd:string |
| http://purl.uniprot.org/citations/26239416 | http://purl.uniprot.org/core/author | "Ge R."xsd:string |
| http://purl.uniprot.org/citations/26239416 | http://purl.uniprot.org/core/date | "2015"xsd:gYear |
| http://purl.uniprot.org/citations/26239416 | http://purl.uniprot.org/core/name | "Mol Immunol"xsd:string |
| http://purl.uniprot.org/citations/26239416 | http://purl.uniprot.org/core/pages | "436-443"xsd:string |
| http://purl.uniprot.org/citations/26239416 | http://purl.uniprot.org/core/title | "IL-23, rather than IL-17, is crucial for the development of ovalbumin-induced allergic rhinitis."xsd:string |
| http://purl.uniprot.org/citations/26239416 | http://purl.uniprot.org/core/volume | "67"xsd:string |
| http://purl.uniprot.org/citations/26239416 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/26239416 |
| http://purl.uniprot.org/citations/26239416 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/26239416 |
| http://purl.uniprot.org/uniprot/#_Q62386-mappedCitation-26239416 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/26239416 |
| http://purl.uniprot.org/uniprot/#_Q544E6-mappedCitation-26239416 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/26239416 |
| http://purl.uniprot.org/uniprot/#_Q9EQ14-mappedCitation-26239416 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/26239416 |
| http://purl.uniprot.org/uniprot/Q544E6 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/26239416 |
| http://purl.uniprot.org/uniprot/Q62386 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/26239416 |
| http://purl.uniprot.org/uniprot/Q9EQ14 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/26239416 |