| http://purl.uniprot.org/citations/26261921 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/26261921 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/26261921 | http://www.w3.org/2000/01/rdf-schema#comment | "The mitotic checkpoint (MC) guards faithful sister chromatid segregation by monitoring the attachment of spindle microtubules to the kinetochores. When chromosome attachment errors are detected, MC delays the metaphase-to-anaphase transition through the inhibition of the anaphase-promoting complex/cyclosome (APC/C) ubiquitin ligase. In contrast to yeast and mammals, our knowledge on the proteins involved in MC in plants is scarce. Transient synchronization of root tips as well as promoter-reporter gene fusions were performed to analyze temporal and spatial expression of COPPER MODIFIED RESISTANCE1/PATRONUS1 (CMR1/PANS1) in developing Arabidopsis thaliana seedlings. Functional analysis of the gene was carried out, including CYCB1;2 stability in CMR1/PANS1 knockout and overexpressor background as well as metaphase-anaphase chromosome status. CMR1/PANS1 is transcriptionally active during M phase. Its deficiency provokes premature cell cycle exit and in consequence a rapid consumption of the number of meristematic cells in particular under stress conditions that are known to affect spindle microtubules. Root growth impairment is correlated with a failure to delay the onset of anaphase, resulting in anaphase bridges and chromosome missegregation. CMR1/PANS1 overexpression stabilizes the mitotic CYCB1;2 protein. Likely, CMR1/PANS1 coordinates mitotic cell cycle progression by acting as an APC/C inhibitor and plays a key role in growth adaptation to stress."xsd:string |
| http://purl.uniprot.org/citations/26261921 | http://purl.org/dc/terms/identifier | "doi:10.1111/nph.13589"xsd:string |
| http://purl.uniprot.org/citations/26261921 | http://purl.org/dc/terms/identifier | "doi:10.1111/nph.13589"xsd:string |
| http://purl.uniprot.org/citations/26261921 | http://purl.uniprot.org/core/author | "De Veylder L."xsd:string |
| http://purl.uniprot.org/citations/26261921 | http://purl.uniprot.org/core/author | "De Veylder L."xsd:string |
| http://purl.uniprot.org/citations/26261921 | http://purl.uniprot.org/core/author | "Heyman J."xsd:string |
| http://purl.uniprot.org/citations/26261921 | http://purl.uniprot.org/core/author | "Heyman J."xsd:string |
| http://purl.uniprot.org/citations/26261921 | http://purl.uniprot.org/core/author | "Verbruggen N."xsd:string |
| http://purl.uniprot.org/citations/26261921 | http://purl.uniprot.org/core/author | "Verbruggen N."xsd:string |
| http://purl.uniprot.org/citations/26261921 | http://purl.uniprot.org/core/author | "Juraniec M."xsd:string |
| http://purl.uniprot.org/citations/26261921 | http://purl.uniprot.org/core/author | "Juraniec M."xsd:string |
| http://purl.uniprot.org/citations/26261921 | http://purl.uniprot.org/core/author | "Schubert V."xsd:string |
| http://purl.uniprot.org/citations/26261921 | http://purl.uniprot.org/core/author | "Schubert V."xsd:string |
| http://purl.uniprot.org/citations/26261921 | http://purl.uniprot.org/core/author | "Salis P."xsd:string |
| http://purl.uniprot.org/citations/26261921 | http://purl.uniprot.org/core/author | "Salis P."xsd:string |
| http://purl.uniprot.org/citations/26261921 | http://purl.uniprot.org/core/date | "2016"xsd:gYear |
| http://purl.uniprot.org/citations/26261921 | http://purl.uniprot.org/core/date | "2016"xsd:gYear |
| http://purl.uniprot.org/citations/26261921 | http://purl.uniprot.org/core/name | "New Phytol."xsd:string |
| http://purl.uniprot.org/citations/26261921 | http://purl.uniprot.org/core/name | "New Phytol."xsd:string |
| http://purl.uniprot.org/citations/26261921 | http://purl.uniprot.org/core/pages | "177-191"xsd:string |
| http://purl.uniprot.org/citations/26261921 | http://purl.uniprot.org/core/pages | "177-191"xsd:string |
| http://purl.uniprot.org/citations/26261921 | http://purl.uniprot.org/core/title | "Arabidopsis COPPER MODIFIED RESISTANCE1/PATRONUS1 is essential for growth adaptation to stress and required for mitotic onset control."xsd:string |
| http://purl.uniprot.org/citations/26261921 | http://purl.uniprot.org/core/title | "Arabidopsis COPPER MODIFIED RESISTANCE1/PATRONUS1 is essential for growth adaptation to stress and required for mitotic onset control."xsd:string |