http://purl.uniprot.org/citations/26292210 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/26292210 | http://www.w3.org/2000/01/rdf-schema#comment | "In order to study the role played by cellular RNA pools produced by homologous genomic loci in defining the transcriptional state of a silenced gene, we tested the effect of non-functional alleles of the white gene in the presence of a functional copy of white, silenced by heterochromatin. We found that non-functional alleles of white, unable to produce a coding transcript, could reactivate in trans the expression of a wild type copy of the same gene silenced by heterochromatin. This new epigenetic phenomenon of transcriptional trans-reactivation is heritable, relies on the presence of homologous RNA's and is affected by mutations in genes involved in post-transcriptional gene silencing. Our data suggest a general new unexpected level of gene expression control mediated by homologous RNA molecules in the context of heterochromatic genes."xsd:string |
http://purl.uniprot.org/citations/26292210 | http://purl.org/dc/terms/identifier | "doi:10.1371/journal.pgen.1005444"xsd:string |
http://purl.uniprot.org/citations/26292210 | http://purl.uniprot.org/core/author | "Pavesi G."xsd:string |
http://purl.uniprot.org/citations/26292210 | http://purl.uniprot.org/core/author | "Corona D.F."xsd:string |
http://purl.uniprot.org/citations/26292210 | http://purl.uniprot.org/core/author | "Onorati M.C."xsd:string |
http://purl.uniprot.org/citations/26292210 | http://purl.uniprot.org/core/author | "Cavalieri V."xsd:string |
http://purl.uniprot.org/citations/26292210 | http://purl.uniprot.org/core/author | "Ingrassia A.M."xsd:string |
http://purl.uniprot.org/citations/26292210 | http://purl.uniprot.org/core/author | "Arancio W."xsd:string |
http://purl.uniprot.org/citations/26292210 | http://purl.uniprot.org/core/date | "2015"xsd:gYear |
http://purl.uniprot.org/citations/26292210 | http://purl.uniprot.org/core/name | "PLoS Genet"xsd:string |
http://purl.uniprot.org/citations/26292210 | http://purl.uniprot.org/core/pages | "e1005444"xsd:string |
http://purl.uniprot.org/citations/26292210 | http://purl.uniprot.org/core/title | "Trans-Reactivation: A New Epigenetic Phenomenon Underlying Transcriptional Reactivation of Silenced Genes."xsd:string |
http://purl.uniprot.org/citations/26292210 | http://purl.uniprot.org/core/volume | "11"xsd:string |
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