| http://purl.uniprot.org/citations/26299618 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/26299618 | http://www.w3.org/2000/01/rdf-schema#comment | "Here we demonstrate that a ubiquitin E3-ligase, FBXO21, targets the multidrug resistance transporter, ABCB1, also known as P-glycoprotein (P-gp), for proteasomal degradation. We also show that the Ser291-phosphorylated form of the multifunctional protein and stem cell marker, CD44, inhibits FBXO21-directed degradation of P-gp. Thus, CD44 increases P-gp mediated drug resistance and represents a potential therapeutic target in P-gp-positive cells."xsd:string |
| http://purl.uniprot.org/citations/26299618 | http://purl.org/dc/terms/identifier | "doi:10.18632/oncotarget.4763"xsd:string |
| http://purl.uniprot.org/citations/26299618 | http://purl.uniprot.org/core/author | "Kaur S."xsd:string |
| http://purl.uniprot.org/citations/26299618 | http://purl.uniprot.org/core/author | "Chan R."xsd:string |
| http://purl.uniprot.org/citations/26299618 | http://purl.uniprot.org/core/author | "Madura K."xsd:string |
| http://purl.uniprot.org/citations/26299618 | http://purl.uniprot.org/core/author | "Lim E."xsd:string |
| http://purl.uniprot.org/citations/26299618 | http://purl.uniprot.org/core/author | "Ravindranath A.K."xsd:string |
| http://purl.uniprot.org/citations/26299618 | http://purl.uniprot.org/core/author | "Wernyj R.P."xsd:string |
| http://purl.uniprot.org/citations/26299618 | http://purl.uniprot.org/core/author | "Miletti-Gonzalez K.E."xsd:string |
| http://purl.uniprot.org/citations/26299618 | http://purl.uniprot.org/core/author | "Rodriguez-Rodriguez L."xsd:string |
| http://purl.uniprot.org/citations/26299618 | http://purl.uniprot.org/core/author | "Kumaran M.N."xsd:string |
| http://purl.uniprot.org/citations/26299618 | http://purl.uniprot.org/core/date | "2015"xsd:gYear |
| http://purl.uniprot.org/citations/26299618 | http://purl.uniprot.org/core/name | "Oncotarget"xsd:string |
| http://purl.uniprot.org/citations/26299618 | http://purl.uniprot.org/core/pages | "26308-26321"xsd:string |
| http://purl.uniprot.org/citations/26299618 | http://purl.uniprot.org/core/title | "CD44 promotes multi-drug resistance by protecting P-glycoprotein from FBXO21-mediated ubiquitination."xsd:string |
| http://purl.uniprot.org/citations/26299618 | http://purl.uniprot.org/core/volume | "6"xsd:string |
| http://purl.uniprot.org/citations/26299618 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/26299618 |
| http://purl.uniprot.org/citations/26299618 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/26299618 |
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| http://purl.uniprot.org/uniprot/#_A8K309-mappedCitation-26299618 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/26299618 |