| http://purl.uniprot.org/citations/26302206 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/26302206 | http://www.w3.org/2000/01/rdf-schema#comment | "Auditory function is dependent on the formation of specific innervation patterns between mechanosensory hair cells (HCs) and afferent spiral ganglion neurons (SGNs). In particular, type I SGNs must precisely connect with inner HCs (IHCs) while avoiding connections with nearby outer HCs (OHCs). The factors that mediate these patterning events are largely unknown. Using sparse-labeling and time-lapse imaging, we visualized for the first time the behaviors of developing SGNs including active retraction of processes from OHCs, suggesting that some type I SGNs contact OHCs before forming synapses with IHCs. In addition, we demonstrate that expression of Semaphorin-3F in the OHC region inhibits type I SGN process extension by activating Neuropilin-2 receptors expressed on SGNs. These results suggest a model in which cochlear innervation patterns by type I SGNs are determined, at least in part, through a Semaphorin-3F-mediated inhibitory signal that impedes processes from extending beyond the IHC region."xsd:string |
| http://purl.uniprot.org/citations/26302206 | http://purl.org/dc/terms/identifier | "doi:10.7554/elife.07830"xsd:string |
| http://purl.uniprot.org/citations/26302206 | http://purl.uniprot.org/core/author | "Kelley M.W."xsd:string |
| http://purl.uniprot.org/citations/26302206 | http://purl.uniprot.org/core/author | "Zhang K.D."xsd:string |
| http://purl.uniprot.org/citations/26302206 | http://purl.uniprot.org/core/author | "Coate T.M."xsd:string |
| http://purl.uniprot.org/citations/26302206 | http://purl.uniprot.org/core/author | "Isgrig K.T."xsd:string |
| http://purl.uniprot.org/citations/26302206 | http://purl.uniprot.org/core/author | "Spita N.A."xsd:string |
| http://purl.uniprot.org/citations/26302206 | http://purl.uniprot.org/core/date | "2015"xsd:gYear |
| http://purl.uniprot.org/citations/26302206 | http://purl.uniprot.org/core/name | "Elife"xsd:string |
| http://purl.uniprot.org/citations/26302206 | http://purl.uniprot.org/core/title | "Neuropilin-2/Semaphorin-3F-mediated repulsion promotes inner hair cell innervation by spiral ganglion neurons."xsd:string |
| http://purl.uniprot.org/citations/26302206 | http://purl.uniprot.org/core/volume | "4"xsd:string |
| http://purl.uniprot.org/citations/26302206 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/26302206 |
| http://purl.uniprot.org/citations/26302206 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/26302206 |
| http://purl.uniprot.org/uniprot/#_A0A0A6YW11-mappedCitation-26302206 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/26302206 |
| http://purl.uniprot.org/uniprot/#_A0A0A6YW56-mappedCitation-26302206 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/26302206 |
| http://purl.uniprot.org/uniprot/#_A0A0G2JDD7-mappedCitation-26302206 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/26302206 |
| http://purl.uniprot.org/uniprot/#_A0A0G2JDP8-mappedCitation-26302206 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/26302206 |
| http://purl.uniprot.org/uniprot/#_A0A0A6YWM9-mappedCitation-26302206 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/26302206 |
| http://purl.uniprot.org/uniprot/#_A0A0A6YWS0-mappedCitation-26302206 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/26302206 |
| http://purl.uniprot.org/uniprot/#_A0A0A6YWW1-mappedCitation-26302206 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/26302206 |
| http://purl.uniprot.org/uniprot/#_A0A0A6YX80-mappedCitation-26302206 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/26302206 |
| http://purl.uniprot.org/uniprot/#_A0A0A6YXC1-mappedCitation-26302206 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/26302206 |
| http://purl.uniprot.org/uniprot/#_A0A0A6YXX2-mappedCitation-26302206 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/26302206 |
| http://purl.uniprot.org/uniprot/#_A0A0A6YY06-mappedCitation-26302206 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/26302206 |