http://purl.uniprot.org/citations/26302971 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/26302971 | http://www.w3.org/2000/01/rdf-schema#comment | "Polymorphisms in interleukin (IL)-18, IL-12 and interferon (IFN)-γ genes are associated with different levels of cytokines expression and have been associated with rheumatoid arthritis (RA). IL-18 +105 A/C, IL-12B +1188 A/C and IFN-γ +874 T/A polymorphisms were analyzed by restriction fragment length polymorphism-polymerase chain reaction (PCR) and amplification refractory mutation system PCR from 90 RA patients and 186 healthy individuals. There were significant differences to IL-18 +105 A/C polymorphism between the RA and control groups (odds ratio = 3.77; P < 0.0001). Individual carriers of the variant allele C had a 3.77-fold increased risk of for RA (P = 0.0032). No association was observed for IL-12B and IFN-γ polymorphisms. Our finds suggest a possible role for IL-18 polymorphism in the RA susceptibility in studied population."xsd:string |
http://purl.uniprot.org/citations/26302971 | http://purl.org/dc/terms/identifier | "doi:10.1111/tan.12645"xsd:string |
http://purl.uniprot.org/citations/26302971 | http://purl.uniprot.org/core/author | "Crovella S."xsd:string |
http://purl.uniprot.org/citations/26302971 | http://purl.uniprot.org/core/author | "Donadi E.A."xsd:string |
http://purl.uniprot.org/citations/26302971 | http://purl.uniprot.org/core/author | "Louzada-Junior P."xsd:string |
http://purl.uniprot.org/citations/26302971 | http://purl.uniprot.org/core/author | "de Souza P.R."xsd:string |
http://purl.uniprot.org/citations/26302971 | http://purl.uniprot.org/core/author | "Oliveira R.D."xsd:string |
http://purl.uniprot.org/citations/26302971 | http://purl.uniprot.org/core/author | "Sandrin-Garcia P."xsd:string |
http://purl.uniprot.org/citations/26302971 | http://purl.uniprot.org/core/author | "Angelo H.D."xsd:string |
http://purl.uniprot.org/citations/26302971 | http://purl.uniprot.org/core/author | "Maia M.M."xsd:string |
http://purl.uniprot.org/citations/26302971 | http://purl.uniprot.org/core/author | "Gomes Silva I.I."xsd:string |
http://purl.uniprot.org/citations/26302971 | http://purl.uniprot.org/core/date | "2015"xsd:gYear |
http://purl.uniprot.org/citations/26302971 | http://purl.uniprot.org/core/name | "Tissue Antigens"xsd:string |
http://purl.uniprot.org/citations/26302971 | http://purl.uniprot.org/core/pages | "276-278"xsd:string |
http://purl.uniprot.org/citations/26302971 | http://purl.uniprot.org/core/title | "Interleukin-18, interleukin-12B and interferon-gamma gene polymorphisms in Brazilian patients with rheumatoid arthritis: a pilot study."xsd:string |
http://purl.uniprot.org/citations/26302971 | http://purl.uniprot.org/core/volume | "86"xsd:string |
http://purl.uniprot.org/citations/26302971 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/26302971 |
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