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| http://purl.uniprot.org/citations/26333836 | http://www.w3.org/2000/01/rdf-schema#comment | "We show that phospholipid anabolism does not occur uniformly during the metazoan cell cycle. Transition to S-phase is required for optimal mobilization of lipid precursors, synthesis of specific phospholipid species and endoplasmic reticulum (ER) homeostasis. Average changes observed in whole-cell phospholipid composition, and total ER lipid content, upon stimulation of cell growth can be explained by the cell cycle distribution of the population. TORC1 promotes phospholipid anabolism by slowing S/G2 progression. The cell cycle stage-specific nature of lipid biogenesis is dependent on p53. We propose that coupling lipid metabolism to cell cycle progression is a means by which cells have evolved to coordinate proliferation with cell and organelle growth."xsd:string |
| http://purl.uniprot.org/citations/26333836 | http://purl.org/dc/terms/identifier | "doi:10.1098/rsob.150093"xsd:string |
| http://purl.uniprot.org/citations/26333836 | http://purl.uniprot.org/core/author | "Zhang Q."xsd:string |
| http://purl.uniprot.org/citations/26333836 | http://purl.uniprot.org/core/author | "Wakelam M.J."xsd:string |
| http://purl.uniprot.org/citations/26333836 | http://purl.uniprot.org/core/author | "Bakal C."xsd:string |
| http://purl.uniprot.org/citations/26333836 | http://purl.uniprot.org/core/author | "Sanchez-Alvarez M."xsd:string |
| http://purl.uniprot.org/citations/26333836 | http://purl.uniprot.org/core/author | "Finger F."xsd:string |
| http://purl.uniprot.org/citations/26333836 | http://purl.uniprot.org/core/date | "2015"xsd:gYear |
| http://purl.uniprot.org/citations/26333836 | http://purl.uniprot.org/core/name | "Open Biol"xsd:string |
| http://purl.uniprot.org/citations/26333836 | http://purl.uniprot.org/core/pages | "150093"xsd:string |
| http://purl.uniprot.org/citations/26333836 | http://purl.uniprot.org/core/title | "Cell cycle progression is an essential regulatory component of phospholipid metabolism and membrane homeostasis."xsd:string |
| http://purl.uniprot.org/citations/26333836 | http://purl.uniprot.org/core/volume | "5"xsd:string |
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